ABSTRACT
The present case report aimed to determine the responsiveness of the endometrium and the ovaries of an X0 mare after hormonal treatment. On transrectal palpation, the uterus was flaccid and smaller than normal, and the ovaries were small and smooth. The endometrium had normal histological architecture, with an atrophic glandular epithelium. A karyotype evaluation was performed, and 70 cells presented 63 chromosomes, lacking one sex chromosome. Circulating hormonal levels of total estrogens were 43.93 pg/mL; progesterone 0.01 ng/mL; testosterone 48 pg/mL; FSH 30.3 ng/mL; and LH 1.71 ng/mL. Immunohistochemistry tests showed the presence of estrogens and progesterone receptors in the endometrial samples of the X0 mare. 17ß estradiol was administrated on three consecutive days and long-action progesterone on the fourth day. After hormonal stimulation, the mare showed changes in endometrial ultrasonography and histology. After treatment with estradiol, uterine edema was noted, and after progesterone, a reduction in edema was observed. At the request of the owner, no further treatment or follow-up occurred. This report showed that the endometrium is functional, but the ovaries did not change macroscopically under hormonal therapy.
Subject(s)
Gonadal Dysgenesis , Horse Diseases , Animals , Estradiol/pharmacology , Estrogens , Female , Gonadal Dysgenesis/veterinary , Horses , Progesterone , Receptors, ProgesteroneABSTRACT
A avaliação científica do bem-estar tem sido importante para detectar animais não adaptados às condições de criação que lhes são impostas, situação que afeta o potencial produtivo e os coloca em maior risco de enfermidades. Com esse objetivo, foram avaliados 30 equinos da Cavalaria da Polícia Militar do Paraná, considerando-se indicadores clínicos, etológicos e hormonais. Na avaliação clínica, além da determinação do escore corporal e exame físico, verificou-se o histórico de ocorrência de cólica nos últimos doze meses. Comportamentos anormais foram pesquisados por observação etológica e a taxa do ritmo circadiano do cortisol (RCC) foi determinada por meio de duas colheitas de sangue, às 08 e às 17 horas. Apesar da significativa ocorrência de comportamentos anormais (26,7%), os achados clínicos foram normais e houve ausência de relato de cólica nos últimos 12 meses precedentes ao estudo. As médias dos resultados das análises de cortisol estiveram dentro da normalidade, nos dados absolutos e na variação do RCC, entretanto, 42% dos animais analisados apresentaram RCC alterado. Apesar da expressiva incidência de comportamentos anormais e de animais com alteração no ritmo circadiano de cortisol, sinais indicadores de estresse crônico, considerou-se que os equinos deste estudo apresentaram boas condições de bem-estar em relação àquelas relatadas por estudos nacionais prévios.
The scientific assessment of welfare has been important to detect animals non adapted to their management conditions, which can interfere with their productive potential and put them at increased risk of illness. With this objective, 30 horses from the Military Police of Paraná were evaluated, considering clinical, ethological and hormonal indicators of equine welfare. In the clinical evaluation, horses were assessed by physical examination and their body score conditions and the history of colic incidence in the last twelve months were determined. Abnormal behavior incidence were studied by ethological observation and the individual rate of circadian rhythm of cortisol (RCC) was calculated based on cortisol concentration changes in two blood samples taken at 08:00 am and 5:00pm. Despite significant incidence of abnormal behaviors (26.7%), clinical findings were normal and there were no reports of colic episodes in the last 12 months preceding the study. The mean blood cortisol concentrations and the mean RCC rate were within the normal range. However, 42% of the studied horses had abnormal RCC rates. Despite the significant incidences of abnormal behavior and abnormal RCC rates (indicators of chronic stress), these horses were considered in good welfare when compared to ones previously reported in other national studies.
