ABSTRACT
BACKGROUND/OBJECTIVE: Psoriatic arthritis (PsA) is a chronic inflammatory illness. Approximately, 15% of psoriasis patients have undiagnosed PsA. In Mexico, we found no related studies. Our objective was to investigate the clinical-epidemiological characteristics of PsA in psoriasis patients in western Mexico. METHODS: A cross-sectional study including Mexican patients with clinical and histopathological diagnosis of psoriasis. Physical examination, rheumatoid factor analysis and radiographies of axial and peripheral skeleton were performed. The prevalence of PsA using the CASPAR criteria, age, sex; clinical variants of PsA, psoriasis type and the Psoriasis Area and Severity Index (PASI), were assessed. Descriptive and inferential statistics were used. RESULTS: Of 90 patients with psoriasis, 48 met the criteria for PsA, with a prevalence of 53%, and average age of 50 ± 15 years. Predominating were, the female sex in 29 (60%), the axial variant of PsA in 24 (50%), and psoriasis plaques in 40 (83%). The average PASI was 12 ± 11. All cases were rheumatoid factor negative. These variables were not significantly different when comparing subjects with and without PsA, except for the female sex (60% vs. 7%; P < 0.001). CONCLUSIONS: Patients with psoriasis should intentionally be evaluated jointly Dermatologists and Rheumatologists searching joint involvement given the high prevalence of PsA previously undiagnosed.
Subject(s)
Arthritis, Psoriatic/diagnosis , Arthritis, Psoriatic/epidemiology , Severity of Illness Index , Adult , Cross-Sectional Studies , Female , Humans , Male , Mexico , Middle Aged , Psoriasis/diagnosis , Psoriasis/epidemiologyABSTRACT
BACKGROUND: Porocarcinoma is a rare tumor, representing 0.005% of all malignant epithelial neoplasms. The majority of publications are single case reports. The objective of this study was to describe the epidemiologic and histopathologic characteristics of patients diagnosed with eccrine porocarcinoma. METHODS: A retrospective study was carried out from January 1994 to December 2010. Cases with a histopathological diagnosis of eccrine porocarcinoma were included. The investigated variables were frequency, gender, age, time of evolution, localization, morphology, referral clinical diagnosis, and histopathology patterns. The information was analyzed using descriptive statistics. RESULTS: During this 17-year period, 33 cases diagnosed with eccrine porocarcinoma were detected. Female gender was predominant with 64% cases. The average age was 74 ± 12 years. The most frequent location was the head with 37% cases; the most common observed morphology was nodular, in 46%. The main referral diagnosis was squamous cell carcinoma in 67% of cases. With regard to the histopathology characteristics, necrosis predominated in 64% cases, comedonecrosis in 45% cases, squamous differentiation in 42% cases, and melanocyte colonization in 21%. CONCLUSIONS: Our series presents some clinical and histopathology differences with previously reported, such as the most frequent localization in the head and the presence of melanocyte colonization.
Subject(s)
Eccrine Porocarcinoma/epidemiology , Eccrine Porocarcinoma/pathology , Sweat Gland Neoplasms/epidemiology , Sweat Gland Neoplasms/pathology , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Retrospective StudiesABSTRACT
Se presenta una reseña del curso de micología médica presentado en Fontilles los días 12 al 15 de noviembre del 2009, para personal médico, paramédico y enfermeras. El objetivo general fue que el alumno sea capaz de adquirir conocimientos necesarios para identificar, prevenir y tratar la micosis subcutáneas, sistémicas y oportunistas. En los últimos años las infecciones producidas por hongos han experimentado una considerable aumento, sobre todo en pacientes inmunosuprimidos. Existen varios factores que favorecen la instauración de la micosis, sobre todo las de tipo profundo como son: cambios climáticos, ecológicos, socio-económicos, migraciones, trasplantes, SIDA, abuso de fármacos entre otros. Lo que ha permitido conocer algunas micosis emergentes con aspectos clínicos atípicos o especies micóticas nuevas (AU)
This is summary of the mycology course held in Fontilles, Spain form the 12th to 15th of November 2009 for medical personnel, paramedics and nurses. Our primary objective was for each attendant to be able to acquire the necessary knowledge to identify, prevent and treat subcutaneous, systemic and opportunistic mycosis. Recently, the infections caused by fungus have increased considerably, especially in inmunodeficient patients. There are various factors that have favored the appearance of mycosis, especially the deep mycosis, factors like: changes in weather, ecology, socioeconomic, migration, transplants, AIDS, pharmacologic abuse and others. All this has allowed us to see emerging mycosis with atypical presentations and new mycotic species (AU)
