Chronic Infection by Plasmodium falciparum.

Malaria by Plasmodium falciparum (P. falciparum) usually does not exceed one year, but chronic infection, although rare, is a possibility. We present the clinical case of a 37-year-old male who came to the emergency department with intermittent fever, chills, and malaise. He had malaria more than 1 year ago while working in Huíla province, Angola. On admission, Plasmodium testing by light microscopy and antigens was negative. Doxycycline was started empirically, but on the third day of hospitalization, he had a new fever spike. Plasmodium DNA and antibodies were tested, confirming P. falciparum. The therapy with artemether-lumefantrine, already after discharge, allowed the consolidation of the treatment and eradicator of the parasite. Detection of parasite DNA by PCR should not be routine, but it is a more sensitive method, which confirmed this chronic infection by P. falciparum after one year.

A Case of Notifiable Alithiatic Cholecystitis.

Acute alithiatic cholecystitis is an inflammation of the gallbladder without evidence of gallstones, often due to infection. It can occur at any age, and it is predominant in males. Listeriosis is a rare bacterial infection caused by Listeria monocytogenes (LM) through the ingestion of contaminated food such as dairy, legumes, and raw meats. Clinical presentations of listeriosis include bacteremia, meningitis, and gastroenteritis. Acute cholecystitis caused by listeria is even more uncommon, with only 23 cases reported in the literature. We present a case of a 65-year-old male, admitted to the Emergency Department with fever and altered state of consciousness which revealed bacteremia due to cholecystitis to LM. The patient was submitted to laparoscopic cholecystectomy and appropriate antibiotic coverage and was discharged seven days later. Early recognition and treatment of this disease are crucial for reducing morbidity and mortality.

Sweet's Syndrome: A Case Report of a Rare Extraintestinal Manifestation of Ulcerative Colitis.

Sweet's syndrome is a neutrophilic dermatosis of unknown etiology and a rare extraintestinal manifestation of ulcerative colitis. Classically, it is more common in women with active inflammatory bowel disease (IBD). This syndrome typically presents in patients with acute-onset painful tender erythematous skin lesions and is usually accompanied by fever, arthralgia, and elevated inflammatory markers. Histological examination is characterized by diffuse dense dermal neutrophilic infiltrate with leukocytoclasia, without vasculitis. The treatment goals are to reduce morbidity and complications, and the most effective therapy is systemic corticosteroids. Early recognition of this syndrome is essential to improve our diagnostic and therapeutic abilities. We report a case of a 59-year-old female with ulcerative colitis, which presented with manifestations of Sweet's syndrome.