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Klin Med (Mosk) ; 69(1): 94-7, 1991 Jan.
Article in Russian | MEDLINE | ID: mdl-2023411

ABSTRACT

Marrow histomorphometry was performed in 73 untreated chronic lymphoid leukemia (CLL) sufferers. Follow-up results are available for 36 of them: 25 treated and 11 untreated with chemotherapy. The method of marrow histomorphometry allows recognition of three CLL forms: diffuse, diffuse-focal and focal; helps to determine indications to chemotherapy, assess its efficacy, prognosticate the disease course; is more reliable than clinical and laboratory findings.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bone Marrow/drug effects , Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy , Lymph Nodes/drug effects , Lymphocytes/drug effects , Adult , Aged , Bone Marrow/pathology , Cyclophosphamide/administration & dosage , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/blood , Leukemia, Lymphocytic, Chronic, B-Cell/pathology , Leukocyte Count/drug effects , Lymph Nodes/pathology , Lymphocytes/pathology , Middle Aged , Prednisone/administration & dosage , Prognosis , Vincristine/administration & dosage
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