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1.
Otolaryngol Head Neck Surg ; 146(2): 203-5, 2012 Feb.
Article in English | MEDLINE | ID: mdl-24436482

ABSTRACT

An impending physician shortage has been projected. The article by Kim, Cooper, and Kennedy, titled "Otolaryngology-Head and Neck Surgery Physician Workforce Issues: An Analysis for Future Specialty Planning," is an attempt to evaluate and address this potential shortage as it applies to otolaryngology. The authors of this comment have concerns about the article's assumptions, design, and recommendations. Kim et al attempt to extrapolate data from other specialties and other countries to the US otolaryngology workforce, use that data in modeling methods without demonstrated validity, and based on their analysis, they recommend drastic changes to otolaryngologic training and practice in the United States. Particularly troublesome are (1) the emphasis placed on gender and part-time work and (2) the measurement of productivity defined as hours worked per week. Before redefining our specialty, more thorough and systematic data acquisition and review are necessary to meet the needs of our patients now and in the future.


Subject(s)
Otolaryngology/organization & administration , Humans , Workforce
2.
Int J Pediatr Otorhinolaryngol ; 73(11): 1499-506, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19346010

ABSTRACT

BACKGROUND: With the increase in new technology and changing indications for tonsillectomy, the literature has exploded during the last 20 years with scores of publications reporting the relative effectiveness of many different techniques. Despite this "wealth of information," no single technique has been adopted by most surgeons. OBJECTIVES: To systematically analyze the usefulness of this literature of the past 20 years concerning tonsillectomy technique in children. To propose the use of specific study parameters that could optimize clinical decision-making and future research. METHODS: Detailed review of the methodologies and findings in articles which compared one or more tonsillectomy techniques in clinical trials of children, ages 1-23 years from 1987 through 2007. RESULTS: The Medline search revealed 255 papers of which 89 studies were suitable for inclusion in our review. In these 89 studies (found in 87 papers), 9 dissection techniques, 3 planes of dissection, 8 methods of hemostasis, and 41 different outcome measures were reported. Forty-four (49%) were described as randomized, 63 (71%) prospective, 25 retrospective (28%), 1 case report, 1 matched pair, and 9 case series papers. Sixteen (18%) trials were non-blind, 23 (26%) were single blind, 17 (19%) were double blind, and 7 (8%) were not stated. Seventy-five (84%) were comparative and 14 (16%) non-comparative. Eight (9%) studies reported power analyses. Twelve (13%) had no follow-up; 67 (75%) of the studies performed had short-term follow-up in the peri-operative period; 10 (11%) had follow-up for greater than 1 year. Eleven (12%) mentioned outcomes related to the effectiveness of the procedure itself in relieving symptoms for which the surgery was done. CONCLUSIONS: Tonsillectomy technique research is of obvious interest to the otolaryngologist. We found deficits in: the precise reporting of surgical techniques, adequate study design and useful outcome measures, all of which make the literature less useful than it could be. Guidelines for study design parameters which could lead to more valuable information for the clinician are suggested.


Subject(s)
Tonsillectomy/methods , Adolescent , Child , Child, Preschool , Humans , Infant , Pharyngeal Diseases/surgery , Publications , Young Adult
3.
Otolaryngol Head Neck Surg ; 140(3): 354-7, 2009 Mar.
Article in English | MEDLINE | ID: mdl-19248942

ABSTRACT

OBJECTIVES: 1) Demonstrate patterns of dog bite injury to the head and neck in children. 2) Identify treatment outcomes of dog bite injuries to the head and neck. STUDY DESIGN: Case series with chart review. SUBJECTS AND METHODS: Children aged 0 to 19 years, treated for head and neck dog bites at our tertiary care children's hospital (1999-2007), were included. Demographics, dog breed and ownership, seasonal incidence, wound location, characteristics, management, and complications were recorded. RESULTS: Eighty-four children, aged 10 months to 19 years (mean, 6.19 years) underwent primary repair of head and neck dog bite injuries. The cheek (34%) and lips (21%) were involved most commonly. Average wound length was 7.15 cm. Dog bite incidence peaked during summer months. Infection occurred in 10.7 percent. Pulsed dye laser was used to improve cosmesis. CONCLUSIONS: Children are vulnerable to head and neck dog bite injuries. Wound healing is excellent despite a contaminated wound. Infections occur infrequently. Pulsed dye laser improves cosmesis.


Subject(s)
Bites and Stings/surgery , Craniocerebral Trauma/surgery , Neck Injuries/surgery , Adolescent , Animals , Child , Child, Preschool , Craniocerebral Trauma/etiology , Debridement , Dogs , Female , Humans , Infant , Male , Neck Injuries/etiology , Retrospective Studies , Wound Healing , Young Adult
4.
J Health Commun ; 14(1): 77-95, 2009.
Article in English | MEDLINE | ID: mdl-19180373

ABSTRACT

Research has begun to explore the determinants of personal digital assistant (PDA) adoption in health care. Much of this research has, however, been inconsistent in its treatment of key constructs and its methodological approaches. The current study takes a stricter approach and tracks the pre- and postadoption beliefs of physicians provided with an actual PDA within a single health care facility in the United States. Results show that age, position in hospital, beliefs about health IT, and cluster ownership are significant, direct predictors of the physician's preadoption beliefs about PDAs. Contrary to prior research findings, both ease of use and usefulness perceptions significantly influenced the physician's intent to adopt PDAs. More important, results show that physicians focus on a broader range of PDA factors during preadoption assessment of the technology, while actual use is based solely on the PDA's ease of use. Moreover, the preadoption usefulness perceptions do not influence postadoption usefulness. Hence, the cognitive and affective determinants of intent to use are seemingly different from those used to evaluate PDA use.


Subject(s)
Attitude of Health Personnel , Attitude to Computers , Computers, Handheld/statistics & numerical data , Diffusion of Innovation , Health Knowledge, Attitudes, Practice , Medical Staff, Hospital/psychology , Adult , Analysis of Variance , Humans , Medical Staff, Hospital/statistics & numerical data , Medicine , Middle Aged , Specialization , United States
5.
Int J Med Inform ; 78(5): 330-9, 2009 May.
Article in English | MEDLINE | ID: mdl-19095496

ABSTRACT

CONTEXT: Medication error prevention is a priority for the U.S. healthcare system in the 21st century. Use of technology is considered by some as critical to achieve this goal. Knowledge of the attitudinal barriers to such adoption, however, is limited. OBJECTIVE: To determine the attitudes of frontline prescriber clinicians towards technology in general, and PDAs specifically, before and after introduction of a PDA in the clinical setting of medication prescribing. DESIGN: A pre- and post-intervention web-based survey, 12-14 months apart. SETTING: Academic tertiary care children's hospital. PARTICIPANTS: Total of 244 prescriber clinicians. INTERVENTION: Distribution of a PDA with pediatric-specific medication prescribing information after completion of an on-line medication safety certification and other safety focused educational sessions. MAIN OUTCOME MEASURES: Ratings (5-point Likert scale) reflecting perceptions and attitudes towards technology in general and technology in medical settings along with self-reported usage of the PDA for Rx. RESULTS: Early Adopters and Late Adopters were identified statistically, and the group membership reflected their prior exposure to and ownership of other technologies. Early Adopters tended to be younger and less experienced clinically (e.g., residents) and more frequent owners and users of technology. Early Adopters expressed significantly more favorable attitudes toward technology and PDAs on both pre- to post-intervention survey occasions. They also utilized the PDA for Rx more often than LAs. Interestingly, PDA use for Early Adopters was based on its ease of use, while PDA use among later adopters was based on its clinical usefulness. CONCLUSIONS: Provision of point of care information using PDAs and a user-friendly, pediatric-specific medication information software package did not positively affect the attitudes of prescriber clinicians among those already favorable toward technology. However, a significant change was found among those with initially less favorable attitudes. Organizations need to understand the nature of both Early and Late Adopters and plan appropriately for managing the respective needs and expectations when potentially beneficial technologies are introduced. In order to ensure the success of an implementation, the training and supportive interventions need to be carefully designed and specifically catered to the personality-based outcome expectations of the prescriber.


Subject(s)
Attitude of Health Personnel , Computers, Handheld , Medical Order Entry Systems , Data Collection , Diffusion of Innovation , Hospitals, Pediatric , Humans , Internet , United States , United States Food and Drug Administration
6.
Int J Pediatr Otorhinolaryngol ; 72(12): 1801-5, 2008 Dec.
Article in English | MEDLINE | ID: mdl-18848362

ABSTRACT

INTRODUCTION: Various surgical techniques are used to manage problematic drooling. These include: (1) re-routing of the submandibular ducts/excision of the sublingual glands (group 1), (2) excision of the submandibular glands/parotid duct ligation (group 2), and (3) ligation of the parotid and submandibular ducts (group 3). PURPOSE: To compare the long-term effectiveness of three surgical techniques and to evaluate long-term caregiver satisfaction. SETTING: Tertiary care children's hospital. STUDY DESIGN: 10 year retrospective chart review and telephone follow-up questionnaire. METHODS: Demographic data, drooling severity, medical management and surgical outcomes using objective severity ratings were evaluated. Satisfaction scores were obtained by phone interview. RESULTS: 33 patients, 19 male and 14 female, age 1.1-27.6 years (mean 9.4+/-4.9) underwent surgery. Six patients were in group 1, 14 in group 2 and 13 patients in group 3. There was no difference in age, sex or severity of drooling among groups. Mean follow-up was 4.5 years (range 1.1-10 years). Post-operative anti-cholinergic use was most common in group 3 (53%) compared to 21% in group 2 and 33% in group 1. Overall caregiver satisfaction for each group was 83% for group 1, 79% for group 2, and 30% for group 3. Gradual return of drooling occurred in 8 of 13 (61%) patients in group 3 and resulted in dissatisfied caregivers. CONCLUSIONS: Although recent literature advocates four-duct ligation, our long-term results do not appear favorable. Reasons for this failure and strategies for avoidance are discussed.


Subject(s)
Caregivers , Outcome Assessment, Health Care , Patient Satisfaction , Salivary Glands/surgery , Sialorrhea/surgery , Adolescent , Adult , Child , Child, Preschool , Cholinergic Antagonists/therapeutic use , Female , Follow-Up Studies , Humans , Infant , Ligation , Male , Recurrence , Retrospective Studies , Severity of Illness Index , Young Adult
7.
Int J Pediatr Otorhinolaryngol ; 72(5): 565-70, 2008 May.
Article in English | MEDLINE | ID: mdl-18295352

ABSTRACT

BACKGROUND: Adenoid "re-growth" is a poorly understood phenomenon. While parents often express concerns regarding the potential for adenoid "re-growth", little information exists in the literature about its incidence and causation. PURPOSE: To establish the incidence and possible contributing factors leading to adenoid re-growth in children. DESIGN: Retrospective case series review. SETTING: Tertiary care children's hospital. METHODS: The charts of 106 patients who underwent revision adenoidectomy between 1995 and 2006 were reviewed. Thirty-four patients were excluded because the primary adenoidectomy was performed elsewhere or initially only a partial adenoidectomy was performed. In the remaining 72 patients, demographic data, clinical presentation, associated medical conditions and findings at surgery were studied. RESULTS: During the 11-year study period. 13,005 adenoidectomies or adenotonsillectomies were performed; 72/13,005 (0.55%) underwent revision adenoidectomy. The mean (+/-S.D.) age at presentation for primary adenoidectomy was 3.68+/-2.9 and 7.69+/-4.04 years for secondary ("revision") adenoidectomy with an average time interval of 4.3 years between surgeries. Age at initial adenoidectomy was not a significant factor in predicting revision adenoid surgery. 29/72 (40%) underwent a reflux work up including scintiscan with gastric emptying, 24h pH probe, or laryngoscopy. 28/29 (96%) were diagnosed with reflux. At least 15/72 (21%) were reported to have symptoms consistent with adenoid re-growth which were found to be caused by tubal tonsil hyperplasia. CONCLUSIONS: Revision adenoidectomy rarely needs to be performed. Tubal tonsillar hyperplasia, as opposed to re-growth of residual adenoid tissue previously removed, accounts for some cases. Extraesophageal reflux is a possible cause in some and requires further study.


Subject(s)
Adenoidectomy , Adenoids/pathology , Airway Obstruction/etiology , Child, Preschool , Female , Humans , Male , Recurrence , Reoperation , Tonsillectomy
8.
Int J Pediatr Otorhinolaryngol ; 72(3): 409-13, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18160139

ABSTRACT

The etiology of adenotonsillar hyperplasia is not well understood. A 3-year-old child presented with obstructive sleep apnea believed to be secondary to enlarged tonsils and adenoids. Subglottic stenosis was encountered during intubation; the adenotonsillectomy was cancelled. Severe extra-esophageal reflux was identified and treated. At follow-up endoscopy 3 weeks later, the tonsils and adenoids were no longer enlarged or obstructing the airway. The role of extra-esophageal reflux in the pathogenesis adenotonsillar hyperplasia is discussed.


Subject(s)
Adenoids/pathology , Gastroesophageal Reflux/complications , Palatine Tonsil/pathology , Adenoidectomy , Adenoids/surgery , Child, Preschool , Humans , Hyperplasia/etiology , Hyperplasia/pathology , Hyperplasia/surgery , Male , Palatine Tonsil/surgery , Tonsillectomy
9.
Ann Otol Rhinol Laryngol ; 116(8): 571-5, 2007 Aug.
Article in English | MEDLINE | ID: mdl-17847723

ABSTRACT

OBJECTIVES: Extraesophageal reflux disease (EERD) is a recognized cause of upper airway symptoms in children. Direct microlaryngoscopy and bronchoscopy (MLB) is performed for diagnostic information as to the extent and severity of the inflammation caused by gastric refluxate. Esophagoscopy with multilevel biopsy performed at the time of MLB may provide the clinician with additional information to assist in the management of EERD. We undertook to determine the role of multilevel esophageal biopsy in children who have airway manifestations secondary to EERD. METHODS: We performed a retrospective chart review of 139 esophagoscopies with multilevel biopsy done at the time of MLB by a single provider for evaluation of symptoms highly associated with EERD at a tertiary care children's hospital. The histopathologic presence of esophagitis was analyzed by site and compared to the presence and location of tracheolaryngeal abnormalities. RESULTS: Tracheolaryngeal abnormalities associated with EERD were found in 97% of patients when evaluated by MLB. Concomitant esophagitis was found in 59% of these patients. Of patients who had 0, 1, 2, 3, 4, or 5 positive findings on MLB, 75% (3 of 4), 58% (7 of 12), 57% (20 of 35), 62% (32 of 51), 56% (18 of 32), and 80% (4 of 5), respectively, had at least 1 positive biopsy. CONCLUSIONS: We found that EERD that affects the pediatric upper airway was associated with esophagitis in more than half of the patients. The usefulness of 4-level biopsies during esophagoscopy and concomitant airway endoscopy will be discussed.


Subject(s)
Biopsy/methods , Esophagitis, Peptic/pathology , Esophagoscopy , Esophagus/pathology , Laryngitis/pathology , Larynx/pathology , Trachea/pathology , Tracheitis/pathology , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Hyperplasia , Infant , Laryngeal Edema/pathology , Laryngostenosis/pathology , Male , Palatine Tonsil/pathology , Retrospective Studies , Tracheal Stenosis/pathology
10.
Int J Pediatr Otorhinolaryngol ; 71(12): 1849-53, 2007 Dec.
Article in English | MEDLINE | ID: mdl-17889942

ABSTRACT

OBJECTIVE: Response to acid suppressive therapy varies in patients with extraesophageal esophageal reflux disease (EERD). Inadequate suppression of gastric acid may contribute to the observed differences in the response to the treatment. The aim of this study was to evaluate suppression of gastric acid in EERD patients being treated with acid suppressive therapy. METHODS: Charts of patients with EERD who underwent dual channel 24h esophageal pH monitoring while receiving acid suppressive therapy between January 2002 and June 2004 were reviewed. Suppression of gastric acid was determined based on the number of acid reflux episodes, esophageal acid exposure, and acid clearance time. RESULTS: Twenty patients (12 male, 8 female, age range: 2-19 years) were identified. Esophageal pH monitoring was within normal limits, documenting complete acid suppression in nine patients (45%). Increased numbers of acid reflux episodes were observed in seven patients. In four patients, the number of acid reflux episodes was normal in spite of incomplete acid suppression. However, other abnormal pH monitoring parameters included delayed acid clearance in three patients and increased acid exposure time in three. The majority of patients also showed alkaline reflux. CONCLUSION: Esophageal pH monitoring documented incomplete acid suppression in this group of infants, children, adolescents and teens with EERD. Monitoring of gastric acid suppression can be useful in guiding the follow-up of EERD patients who receive acid suppressive therapy.


Subject(s)
Esophagitis, Peptic/drug therapy , Gastric Acid/metabolism , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Hydrogen-Ion Concentration , Male
11.
Int J Pediatr Otorhinolaryngol ; 71(9): 1361-9, 2007 Sep.
Article in English | MEDLINE | ID: mdl-17644193

ABSTRACT

OBJECTIVE: The role of laryngopharyngeal reflux (LPR) in hoarseness in children is not well studied. The purpose of this study was to determine the prevalence of LPR in hoarse children. METHODS: Retrospective chart review identified 337 children with hoarseness over a 3-year period. DATA COLLECTED: mode of presentation, associated symptoms, endoscopic findings, laboratory testing, and therapeutic interventions and their outcomes. RESULTS: Mean age at presentation was 7.2+/-4.3 years with a male:female ratio of 1.7:1. Of the 295/337 (88%) children who underwent endoscopy, 107/295 (36%) had LPR changes alone, 86/295 (29%) had vocal fold nodules, 63/295 (20%) had both LPR and vocal fold nodules; and 22/295 (7%) had a finding other than LPR or nodules. Of the children diagnosed with LPR by endoscopy (with or without nodules), 93/170 (55%) underwent at least one additional test for reflux with 69/93 (74%) having a positive test. Of the children diagnosed with LPR by endoscopy, neither cough nor throat clearing was identified in 82/170 (48%) of children. At the first follow-up visit, an average of 3 months from initial presentation, 50% of 169 children who were treated for reflux had improved or resolved. By the second follow-up visit, 4.5 months later, 68% of those children had improved or resolved. CONCLUSIONS: LPR appears to be a very common cause of hoarseness in children, and is an increasingly important symptom in identifying children with LPR. Treatment of LPR often results in improvement of hoarseness.


Subject(s)
Gastroesophageal Reflux/complications , Gastroesophageal Reflux/epidemiology , Hoarseness/epidemiology , Hoarseness/etiology , Child , Cough/diagnosis , Cough/epidemiology , Female , Gastroesophageal Reflux/physiopathology , Hoarseness/physiopathology , Humans , Laryngoscopy , Larynx/physiopathology , Male , Pharynx/physiopathology , Prevalence , Retrospective Studies , Severity of Illness Index
12.
Curr Opin Otolaryngol Head Neck Surg ; 14(6): 387-92, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17099345

ABSTRACT

PURPOSE OF REVIEW: To summarize and contextualize current concepts in the incidence, diagnosis, management and long-term sequelae of extraesophageal reflux disease in children. RECENT FINDINGS: Extraesophageal reflux disease is a different disease entity from gastroesophageal reflux disease. The two diseases have a common etiology, refluxate causing mucosal damage, but the extent and location of the damage varies considerably depending on the underlying mucosal characteristics. Extraesophageal reflux disease in children is characterized by a broad set of symptoms and signs that vary according to age at presentation and severity of disease. Serious long-term effects begin in childhood. The role of pepsin, bile acids, pancreatic enzymes, motility disorders, and food allergies have only recently been recognized. Newer diagnostic modalities include multichannel intraluminal pH/impedance, the 48 h Bravo implantable probe, and hypopharyngeal pH monitoring. While proton pump inhibitors provide superior acid suppression compared with histamine-2 blockers, variability in response and lack of efficacy for alkaline refluxate often require other therapeutic interventions. SUMMARY: Pediatric extraesophageal reflux disease has variable presentation and a gold standard test is still lacking. Primary treatment includes lifestyle and feeding changes and medical therapy. Ongoing monitoring for recurrence and agreement as to duration of therapy present significant challenges not yet standardized amongst practitioners.


Subject(s)
Gastroesophageal Reflux , Adolescent , Adult , Child , Child, Preschool , Gastroesophageal Reflux/complications , Gastroesophageal Reflux/diagnosis , Gastroesophageal Reflux/therapy , Humans , Infant
13.
Pediatrics ; 118(4): e1124-9, 2006 Oct.
Article in English | MEDLINE | ID: mdl-17015504

ABSTRACT

BACKGROUND: Medication management is a complex, multifaceted system. Prescribing errors occur upstream in the process, and as such, their effects can be perpetuated, and sometimes even exacerbated, in subsequent steps. These errors place patients at risk of adverse drug events. Children, especially young infants, are at particular risk because of their size, unique physiology, and immature ability to metabolize drugs. OBJECTIVE: The purpose of this study was to reduce the risk of harm to children resulting from prescribing errors. METHODS: We sequentially implemented patient safety initiatives over a 1-year time frame at a pediatric tertiary care academic facility. The initiatives included an educational Web site with competency examination, distribution of a personal digital assistant-based standardized dosing reference, a zero-tolerance policy for incomplete or incorrect medication orders, prescriber performance feedback, and presentation of outcome data at citywide grand rounds. A total of 8718 orders were collected and analyzed to assess the impact of these initiatives. RESULTS: The absolute risk reduction from prescribing errors was 38 per 100 orders, with a relative risk reduction of 49%. Web-based education with point-of-care drug references and a zero-tolerance policy for incomplete or incorrect orders were most effective in decreasing potential adverse drug events. Documentation of appropriate weight-based dosing and indication for therapy increased by 24% and 42%, respectively. CONCLUSIONS: Process-improvement initiatives focusing on prescriber education and behavior modification can reduce the risk of harm to pediatric patients from prescribing errors.


Subject(s)
Computers, Handheld , Hospitals, Teaching/standards , Medical Records Systems, Computerized , Medication Errors/prevention & control , Pediatrics/standards , Point-of-Care Systems , Child , Clinical Competence , Drug Prescriptions , Drug-Related Side Effects and Adverse Reactions , Humans , Internet , Risk Management
14.
Int J Pediatr Otorhinolaryngol ; 69(11): 1555-7, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16191440

ABSTRACT

A constellation of otolaryngologic signs and symptoms has been suggested to identify the association between extraesophageal reflux disease (EERD) and pediatric otolaryngologic disorders. We describe chronic nasal pain as a manifestation of laryngopharyngeal acid reflux in a 4-year-old boy who presented with frequent night awakenings due to severe nasal pain. His presentation, relevant history physical examination, diagnostic studies, and response to therapy are described. This is the first report documenting nasal pain resolved with acid suppressive therapy in a child with EERD. The incidence and pathogenesis of EERD induced nasal symptoms in children merits further investigation.


Subject(s)
Gastroesophageal Reflux/diagnosis , Nasal Cavity/physiopathology , Pain/etiology , Sleep Initiation and Maintenance Disorders/etiology , 2-Pyridinylmethylsulfinylbenzimidazoles , Anti-Ulcer Agents/therapeutic use , Child, Preschool , Diet , Gastroesophageal Reflux/therapy , Histamine H2 Antagonists/therapeutic use , Hoarseness/etiology , Humans , Lansoprazole , Life Style , Male , Omeprazole/analogs & derivatives , Omeprazole/therapeutic use , Pain/physiopathology , Proton Pump Inhibitors , Ranitidine/therapeutic use , Sleep Initiation and Maintenance Disorders/physiopathology , Snoring/etiology
15.
Int J Pediatr Otorhinolaryngol ; 69(8): 1109-12, 2005 Aug.
Article in English | MEDLINE | ID: mdl-15878205

ABSTRACT

OBJECTIVE: To determine if the presence of laryngeal pseudosulcus is a good predictor of reflux in children. METHODS: A retrospective review of clinical photographs of 66 children undergoing direct laryngoscopy for airway symptoms for the presence of laryngeal pseudosulcus. Its presence was correlated with positive reflux tests: 24 h pH monitoring, gastric scintiscan, barium swallow, and esophageal biopsy. RESULTS: Fifty-six patients had a positive reflux test, and 89% of these had pseudosulcus. Seventy percent of the reflux-negative group (N=10) had no pseudosulcus. Sensitivity and specificity were 89% and 70%, respectively. CONCLUSIONS: On its own the presence of pseudosulcus has marginal predictive use, but it is found more frequently among reflux-positive children and may be a useful marker to add to existing visual scoring systems.


Subject(s)
Gastroesophageal Reflux/complications , Gastroesophageal Reflux/diagnosis , Laryngeal Edema/diagnosis , Laryngeal Edema/etiology , Adolescent , Bronchoscopy , Child , Child, Preschool , Female , Gastric Acidity Determination , Humans , Infant , Laryngoscopy , Male , Predictive Value of Tests , Retrospective Studies , Sensitivity and Specificity
16.
Int J Pediatr Otorhinolaryngol ; 69(5): 597-605, 2005 May.
Article in English | MEDLINE | ID: mdl-15850681

ABSTRACT

OBJECTIVE: Recurrent respiratory papillomatosis (RRP) is a benign infectious disease which is caused by the human papilloma virus (HPV). When it infects the larynx, hoarseness and airway obstruction are often the presenting symptoms. Latent virus is found in the laryngeal mucosa of many more patients than exhibit the disease. The factors which lead to virus activation have not been identified, however, extra-esophageal acid reflux disease (EERD) has been suggested as one of these factors. METHODS: This is a case series of four patients with RRP who had increase in severity of their disease with the recognition of concurrent extra-esophageal acid reflux. The clinical course of the papillomatosis and the diagnosis and treatment of reflux are compared over time. RESULTS: In all four cases, with identification and treatment of the EERD, control of the RRP improved, and in at least two patients, was complete with resolution of the EERD. Lapses in compliance with medications or behavioral and dietary recommendations in three out of four patients led to a rebound in symptoms and signs of RRP, including worsening of vocal quality and the endoscopic appearance of the larynx. CONCLUSION: The clinical course of these patients suggests a link between the presence of EERD and RRP. The inflammation induced by chronic acid exposure may result in the expression of HPV in susceptible tissues. Prompt diagnosis and effective treatment of EERD should be considered in all patients with difficult to control RRP or with clinical presentation or endoscopic signs of EERD.


Subject(s)
Gastroesophageal Reflux/complications , Gastroesophageal Reflux/diagnosis , Laryngeal Neoplasms/complications , Neoplasm Recurrence, Local/complications , Papilloma/complications , Airway Obstruction/etiology , Airway Obstruction/therapy , Child , Child, Preschool , Gastroesophageal Reflux/therapy , Humans , Laryngeal Neoplasms/therapy , Laryngeal Neoplasms/virology , Male , Neoplasm Recurrence, Local/therapy , Papilloma/therapy , Papilloma/virology , Papillomaviridae , Papillomavirus Infections/complications , Papillomavirus Infections/therapy , Severity of Illness Index , Tumor Virus Infections/complications , Tumor Virus Infections/therapy
17.
Pediatr Crit Care Med ; 5(2): 124-32, 2004 Mar.
Article in English | MEDLINE | ID: mdl-14987341

ABSTRACT

OBJECTIVE: To evaluate a matrix for determining the predominant type, cause category, and rate of medication prescribing errors, and to explore the effectiveness of hospital-based improvement initiatives among pediatric intensive care units (PICUs). DESIGN: This study involved the prospective identification of medication errors for categorization and evaluation by using a matrix methodology. A pretest-posttest design without a control group was used to explore the impact of initiatives employed to reduce medication error rates and severity. SETTING: PICUs in nine freestanding, collaborating tertiary care children's hospitals that participated in both baseline and postintervention analyses. METHODS: We evaluated 12,026 PICU medication orders at baseline and 9,187 orders postintervention for prescribing errors, excluding resuscitation orders. A standardized tool and process captured error type, cause category, and severity for 2 wks before and after intervention. Three levels of error detection were used and included pharmacy order entry, PICU nurse order transcription, and team-based overview. Site-specific interventions were implemented, which included predominantly provider education as well as informational (47%) and dosing "assists" via preprinted orders, forcing functions, or prompts (39%). RESULTS: Of baseline orders, 11.1% had at least one prescribing error. The interception of prescribing errors improved 30.9% (1.6% of all orders at baseline, 2.0% post intervention). Preventable adverse drug events were uncommon (0.6% of all medication errors) and of low severity at baseline; most were wrong dose errors. The implementation of improvement initiatives, specific for each facility, resulted in a 31.6% reduction in prescribing errors from 11.1% to 7.6%. However, site results varied considerably. CONCLUSIONS: A benchmark for medication prescribing errors in the PICU was identified among nine children's hospitals. The methodology was successful in accounting for site-specific differences with regard to identifying and documenting errors as well as reporting results of improvement initiatives. Furthermore, the methodology employed was generalizable in the identification of predominant prescribing error types, which helped to track individual hospital improvement initiative development and implementation. Overall improvement in prescribing error rates was noted; however, considerable variation in the success of improvement initiatives was noted and bears further attention.


Subject(s)
Intensive Care Units, Pediatric/statistics & numerical data , Medication Errors/classification , Medication Errors/statistics & numerical data , Quality Assurance, Health Care/methods , Drug Therapy, Computer-Assisted/methods , Humans , Medication Systems, Hospital/statistics & numerical data , Nurses , Pharmacy Service, Hospital , Prospective Studies
18.
Arch Otolaryngol Head Neck Surg ; 129(8): 825-8, 2003 Aug.
Article in English | MEDLINE | ID: mdl-12925339

ABSTRACT

BACKGROUND: Laser-assisted tympanic membrane fenestration (LTMF) provides intermediate-duration middle ear ventilation, which benefits selected children with acute otitis media (AOM) and otitis media with effusion (OME). OBJECTIVE: To evaluate clinical and technical factors that may affect duration of LTMF patency. DESIGN: Prospective clinical cohort effectiveness trial. SETTING: Four tertiary care children's hospitals. PATIENTS: Volunteer sample of 251 children (430 ears) followed up at 1, 2, 3, 4, 8, and 12 weeks; time to fenestration closure was evaluable in 201 ears, and assessment of cure at study conclusion was evaluable in 128 ears. INTERVENTIONS: Laser-assisted tympanic membrane fenestration for prospectively defined AOM or OME. The surgeon determined spot size, wattage, and concurrent adenoidectomy based on clinical judgment. MAIN OUTCOME MEASURES: Cure of AOM/OME with effusion at 90 days and duration of LTMF patency relative to spot size (1.8-2.8 mm), fenestration location on tympanic membrane, power (7-22 W), concurrent adenoidectomy, age, diagnosis (AOM vs OME), type of effusion, and preoperative tympanogram characteristics. Results are based on the number of ears that could be evaluated at each data collection interval. RESULTS: Fenestrations remained patent for 2 to 4 weeks (mean = 2.52, median = 2.0, SD = 1.4, n = 201); 97.4% were closed at 6-week follow-up. Spot sizes of 2.4 and 2.6 mm had a higher rate of patency than 2.0-mm spot size at 3 weeks following LTMF. Cure at 90 days was related to duration of patency for all patients combined and for patients treated for AOM and OME, but not for those undergoing adjunctive adenoidectomy. Cure at 90 days was related to larger spot size for all patients combined and those treated for AOM. Other investigated factors did not achieve statistical significance. CONCLUSIONS: Spot size of 2.4 mm or greater results in improved duration of LTMF patency, persisting for up to 3 weeks after LTMF, especially for treatment of AOM. Increased duration of LTMF patency correlates with greater incidence of cure of middle ear effusion at 90 days. Additional investigation is indicated to determine optimum spot size and optimum duration of patency for disease- severity-adjusted populations.


Subject(s)
Laser Therapy/methods , Middle Ear Ventilation/methods , Otitis Media with Effusion/surgery , Otitis Media/surgery , Tympanic Membrane/surgery , Acute Disease , Chi-Square Distribution , Child , Female , Humans , Male , Otitis Media/diagnosis , Otitis Media with Effusion/diagnosis , Prospective Studies , Treatment Outcome
19.
J Laryngol Otol ; 116(7): 499-501, 2002 Jul.
Article in English | MEDLINE | ID: mdl-12238667

ABSTRACT

The presence of Streptococcus pneumoniae in chronic otitis media was determined with a new antigen detection kit, the NOW test. The NOW test was originally designed as a urinary antigen test but was adapted to middle-ear effusions for the present study. Middle-ear effusions from 52 children were studied. Streptococcus pneumoniae was cultured from 10 per cent of the effusions. The NOW test was positive in 23 per cent of the effusions, 80 per cent of culture positive and 17 per cent of culture negative effusions. The NOW test proved to be rapid, simple, reliable and relatively inexpensive for the detection of pneumococcal antigen in the middle-ear effusions. This test may prove valuable for the management of children with acute otitis media who undergo tympanocentesis.


Subject(s)
Otitis Media with Effusion/microbiology , Pneumococcal Infections/diagnosis , Streptococcus pneumoniae/isolation & purification , Antigens, Bacterial/analysis , Bacteriological Techniques , Child , Child, Preschool , Chronic Disease , Female , Humans , Infant , Male , Reagent Kits, Diagnostic , Streptococcus pneumoniae/immunology
20.
Laryngoscope ; 112(4): 612-5, 2002 Apr.
Article in English | MEDLINE | ID: mdl-12150511

ABSTRACT

OBJECTIVES: To evaluate the diagnostic accuracy and satisfaction of patient or family (or both) in the evaluation of hemangiomas and other vascular malformations. STUDY DESIGN: Prospective, relational database. METHODS: Ninety-eight patients participated in a prospective, Institutional Review Board-approved, relational database study in the Hemangioma and Vascular Birthmark Center at the Children's Hospital of Buffalo (Buffalo, NY) from July 1998 to April 2000. This included 68 patients with hemangiomas and 30 with vascular malformations. Data regarding presenting and final diagnosis and satisfaction of patient or family (or both) were obtained. RESULTS: Analysis of diagnostic accuracy revealed a concurrence between initial and final combined clinical and magnetic resonance imaging-based diagnosis in only 37% of cases. Analysis of patient and family satisfaction with the care received from previous consultants revealed only 26% "entirely" satisfied, 26% "somewhat" satisfied, and 37% "not at all" satisfied. On average, 2.5 (SD = 1.6; range, 1-9; median, 2) different physicians saw the patient before the patient or family (or both) was satisfied. CONCLUSIONS: Accurate diagnosis of hemangiomas and vascular malformations remains a challenge for physicians. Confusing terminology, lack of knowledge regarding lesion behavior, and poorly understood diagnostic criteria by physicians are some of the reasons for patient frustration. Education of primary care providers through improved communication helps to optimize a coordinated, interdisciplinary approach to patients and their families who present with vascular anomalies.


Subject(s)
Arteriovenous Malformations/diagnosis , Hemangioma/diagnosis , Child, Preschool , Databases, Factual , Female , Humans , Infant , Infant, Newborn , Male , Patient Satisfaction , Prospective Studies
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