Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 14 de 14
Filter
1.
Article in Spanish | IBECS | ID: ibc-81844

ABSTRACT

La conquista de la dignidad es lo que merece toda persona humana por el mero hecho de serlo, con todas y cada una de las particularidades y de las diferencias y esto es aplicable también a las personas con discapacidad. Además, el respeto dignifi ca a quien lo siente y lo practica. La bioética pone a nuestro alcance un análisis crítico y razonado sobre nuestro comportamiento, para conocer los valores en los que basamos nuestras actuaciones. La ética que la sustenta no es ningún moralismo, sino una refl exión racional sobre lo que hacemos y por qué lo hacemos. Se trata, de ir adquiriendo una mayor conciencia para poder progresar y ayudar a hacerlo. Progreso y salud son conceptos muy vinculados a la idea de emancipación personal. Para considerar esta autoconstrucción es preciso saber verla como un esfuerzo, siempre admirable, para aprovechar la oportunidad de vivir. Este esfuerzo merece disfrutar de los derechos a la protección general: a la no discriminación, la privacidad y la confi dencialidad, la expresión de autonomía con la forma y la limitación que se tenga. La solidaridad y la ayuda personalizada es un acompañamiento sensible a las necesidades personales y cambiantes. Acompañar no es caminar en el lugar del otro, sino saber estar y caminar a su lado, “estar a su lado”. Si nos tomamos en serio los derechos humanos, de todos las personas, sea cual sea su característica, veremos que las preguntas que nos tenemos que plantear tienen que ser numerosas, cotidianas y valientes (AU)


The conquering of dignity is the consideration which all human beings deserve simply for what we are in each and every one of the particularities and differences which defi ne us; applicable to persons with disabilities as much as the rest. In addition, respect dignifi es those who feel and show it. Bioethics would like to put within our reach a habit of critical thinking and reasoned analysis of our behaviour, to identify the values on which we base our actions. The ethics sustaining it by no means correspond to moralism, rather a rational consideration of what and why we do something. It is a question of acquiring greater awareness in order to be able to progress and help with this. Progress and health as concepts are closely linked to the idea of personal emancipation. To consider this self-construction, it is a question of seeing it as an effort, always admirable, to take advantage of the opportunity to live. This effort deserves to enjoy entitlement to general protection, i.e., lack of-discrimination, privacy and confi dentiality: an expression of autonomy taking the form it takes and having limitations. The help which everyone needs must be a companion sensitive to personal and changing needs. Accompanying does not mean walking in somebody else’s place, nor overtaking them, but knowing how to be with someone and walk “by their side”. If we take seriously human rights of all humans whatever their characteristics, then we will see that the questions we should ask ourselves are numerous, daily and requiring courage (AU)


Subject(s)
Humans , Male , Female , Child , Bioethics/education , Bioethics/trends , Bioethical Issues/standards , Human Rights/education , Human Rights/psychology , Human Rights/statistics & numerical data , Human Rights/standards , Human Rights/trends , Disability Evaluation , Ethics
2.
J Invest Surg ; 18(1): 13-8, 2005.
Article in English | MEDLINE | ID: mdl-15804947

ABSTRACT

Pancreatic islet transplantation has been proposed as an attractive option for the treatment of type I diabetes. Transplantation into different sites has been investigated, among them those that are immuno-logically privileged (e.g., thymus, uterus, brain, anterior eye chamber, and testicle). Because of their characteristics, seminal vesicles could be considered as immunologically privileged organs, but there is no worldwide experience that can confirm it. The purpose of the present study is to assess the viability and functionality of islet transplantation into seminal vesicles of diabetic rats. One hundred ninety inbred adult male syngeneic Lewis rats were used as donors (n = 72), receptors (n = 36), and controls(n = 11). Diabetes was chemically induced through a single intraperitoneal injection of streptozotocin. Groups of 1200 purified islets were introduced in the right seminal vesicle of diabetic rats. Diabetic control rats were sham transplanted. Body weight and glycemia were monitored every 2 d. Of transplanted rats, 16.7% achieved a good function due to islet engraftment, while 30.6% achieved a partially good response, and 52.7% were considered as nonresponding. This is the first report about islet transplantation into seminal vesicles of diabetic animals. Our results indicate that islet transplantation into rat seminal vesicles is technically possible, and that islets can function normally after engraftment into the wall of the seminal vesicle.


Subject(s)
Diabetes Mellitus, Experimental/surgery , Graft Survival , Islets of Langerhans Transplantation/methods , Seminal Vesicles/surgery , Animals , Blood Glucose , Body Weight , Diabetes Mellitus, Experimental/blood , Hyperglycemia/blood , Hyperglycemia/surgery , Male , Rats , Rats, Inbred Lew
4.
Ann Oncol ; 11(6): 701-5, 2000 Jun.
Article in English | MEDLINE | ID: mdl-10942059

ABSTRACT

BACKGROUND: Sentinel node biopsy (SNB) has been proposed as an alternative to axillary lymph-node dissection (ALND) in breast cancer. Before implementing SNB in our practice, we wished to test its validity by comparing it to the standard ALND, both in our hands and with other reported series. PATIENTS AND METHODS: One hundred thirty-two patients were included prospectively. SNB and immediate ALND were performed. For SNB, a technetium-colloid was used to produce preoperative lymphoscintigraphy and intraoperative gamma-probe search for the SN. Serial sectioning and immunostains were used on the SN. A comprehensive review of the literature was done in order to run a meta-analysis of diagnostic tests using a summary receiver operating characteristic curve (SROC) to calculate the pooled parameters of sensitivity and associated 95% confidence interval (95% CI), including our own data. RESULTS: Our technical success rate was 96%. Local sensitivity was 96%, with a 95% CI from 85%-99%. Seven patients were upstaged by the SNB. A literature search identified 18 studies published from 1996-1999. Estimates of sensitivity ranged from 83%-100%. The pooled data meta-analysis gave a global sensitivity of 91%, with a 95% CI from 89%-93%. The area under the global SROC curve was 0.9967. CONCLUSIONS: The minimally invasive SNB was shown to be a practical alternative to ALND. We propose to use local as well as global sensitivity and associated 95% CI to test the validity of SNB in the clinical setting. Due to limitations of ALND as the golden standard, SNB can in fact be considered a more accurate method for nodal staging.


Subject(s)
Breast Neoplasms/pathology , Lymph Node Excision , Sentinel Lymph Node Biopsy , Adult , Aged , Aged, 80 and over , Axilla , Female , Humans , Middle Aged , Prospective Studies , ROC Curve , Sensitivity and Specificity , Technetium
5.
Arch Surg ; 133(2): 189-93, 1998 Feb.
Article in English | MEDLINE | ID: mdl-9484733

ABSTRACT

OBJECTIVES: To study the incidence of band erosion in patients who have undergone vertical banded gastroplasty and to describe the reparative techniques used. DESIGN: A retrospective review case series. SETTING: A university hospital-based tertiary referral center. PATIENTS: Two hundred fifty consecutive morbidly obese patients who underwent vertical banded gastroplasty between 1987 and 1995. MAIN OUTCOME MEASURES: The development of band erosion into the stomach, reparative surgical techniques, and long-term weight loss control. RESULTS: Band erosion developed in 7 (2.8%) of the patients. Two patients had symptoms 1 month after undergoing forced endoscopy. Six patients required reoperation. The operative findings included 2 cases of "external" band erosion through the lesser curvature into the stomach and 4 cases of "internal" band erosion through the circular staple line. The surgical techniques used for repair depended on the radiological and endoscopic data and on the operative findings; the techniques included conversion into a gastric bypass, band replacement after the creation of a new stoma, and gastroplasty plus distal gastric bypass. There were no complications, and adequate long-term weight loss was achieved in all but 1 of the patients who underwent reoperation. CONCLUSION: Band erosion may be corrected using appropriate surgical techniques to allow for adequate long-term weight loss in patients who have undergone vertical banded gastroplasty.


Subject(s)
Gastroplasty/methods , Adult , Female , Humans , Incidence , Male , Middle Aged , Obesity, Morbid/surgery , Reoperation , Retrospective Studies , Treatment Outcome
7.
Nutr Hosp ; 10(6): 307-20, 1995.
Article in Spanish | MEDLINE | ID: mdl-8599615

ABSTRACT

UNLABELLED: Obesity as a condition, and morbid obesity as a disease, have at present reached epidemic proportions. Bariatric surgery is the most effective treatment in those patients in whom medical, dietary, and/or behavioral treatments have failed. What is more, it is the initial treatment of choice in morbid superobese patients (> 50 kg/m2). The present study summarizes and criticizes the main surgical techniques used at present, and purposes an action protocol for anesthesia, as well as some norms and advice on control, action, and pulmonary and dietary rehabilitation, in the peri- and post operative period, based on more than 7 years' experience with a series of more than 150 operated and controlled patients. CONCLUSION: A restrictive bariatric technique is a model which allows the multidisciplinary obesity treatment team to achieve a definite and permanent modification of the eating habits of all patients who meet the criteria for inclusion in a surgical protocol.


Subject(s)
Intraoperative Care , Obesity, Morbid/surgery , Anesthesia/methods , Body Mass Index , Clinical Protocols , Diet, Reducing , Female , Humans , Intraoperative Care/methods , Male , Obesity, Morbid/diagnosis , Postoperative Care/methods
8.
Nutr Hosp ; 10(6): 321-30, 1995.
Article in Spanish | MEDLINE | ID: mdl-8599616

ABSTRACT

Bariatric surgery is done on a selected, ill patient (morbid obesity), with a surgical risk which is intrinsic to his condition and morbidity. The results on any program are more a function of the adequate selection, information and control, than of the surgical model itself. The first 125 patients of the present surgical series have been reviewed, with a minimum of 18 months of follow up, and the complications are detailed, with emphasis on the compulsory and necessary radiological evaluation in the immediate post-operative period, during the follow up, and in the face of any complication. The effectiveness criteria of the technique and the real value of the weight loss are reevaluated, as well as defining the criteria of failure of surgical treatment. Finally, we end with an up dating of the psychological results observed, as well justifying the need for a bariatric surgery protocol, with its ethical-legal implications. The final conclusion is that bariatric surgery shall only be clinically and ethically accepted if it complies with the principles for which it was designed.


Subject(s)
Obesity, Morbid/surgery , Anthropometry , Clinical Protocols , Female , Follow-Up Studies , Humans , Informed Consent , Male , Obesity, Morbid/complications , Obesity, Morbid/diagnosis , Obesity, Morbid/psychology , Postoperative Complications/epidemiology , Weight Loss
10.
Hepatology ; 20(2): 370-5, 1994 Aug.
Article in English | MEDLINE | ID: mdl-7913907

ABSTRACT

Somatostatin and endoscopic sclerotherapy are widely used in the treatment of acute variceal bleeding. Although objective evidence does exist about the advantages of either treatment, data comparing both procedures are scarce. In order to compare the effectiveness and safety of somatostatin and sclerotherapy in the treatment of acute variceal bleeding, 70 consecutive cirrhotic patients suffering from esophageal variceal hemorrhage and meeting the inclusion criteria were randomly assigned to treatment with somatostatin (35 patients) or sclerotherapy (35 patients). No differences in age, sex, alcohol intake, etiology of cirrhosis and severity of liver failure were found between groups. Failure of treatment (defined as persistence of bleeding despite therapy or subsequent rebleeding within the 48-hr trial period) occurred in seven patients (20%) in the somatostatin group and in six (17.1%) in the sclerotherapy group (NS). Early rebleeding occurred in seven of 28 patients (25%) in the somatostatin group and in five of 29 (17.2%) in the sclerotherapy group (NS). Mortality within the first 6 wk was no different between both groups: 10 (28.5%) and eight (22.8%) in the somatostatin and sclerotherapy groups, respectively. Sclerotherapy, but not somatostatin, was associated with major complications in five cases (14.2%) (p = 0.026), two of which resulted in patient's death. These results suggest that somatostatin is safer, and as effective as sclerotherapy, in controlling acute variceal bleeding until an elective treatment can be established.


Subject(s)
Esophageal and Gastric Varices/therapy , Gastrointestinal Hemorrhage/therapy , Sclerotherapy , Somatostatin/therapeutic use , Acute Disease , Esophageal and Gastric Varices/drug therapy , Esophageal and Gastric Varices/mortality , Female , Gastrointestinal Hemorrhage/drug therapy , Gastrointestinal Hemorrhage/mortality , Humans , Male , Middle Aged , Multivariate Analysis , Prospective Studies , Recurrence , Sclerotherapy/adverse effects , Survival Rate
11.
Med Clin (Barc) ; 99(12): 444-9, 1992 Oct 17.
Article in Spanish | MEDLINE | ID: mdl-1460895

ABSTRACT

BACKGROUND: In the present study the year experience of a multidisciplinary team (oncologic, unit for the acquired immunodeficiency syndrome, and surgery) with the use of a new method of central intravenous administration of medication such as that of subcutaneous venous reservoirs (SVR) is reviewed. METHODS: The subcutaneous injection capsules were implanted as a venous access in 150 surgical procedures in 146 patients from October 1985 to April 1991 with a total follow up of 29.190 days and a mean length of 251 days for SVR. Sixty-two percent (94 implantations) of the SVR were implanted in the out patient clinic, 20% (30 patients) were admitted for placement of the reservoir although this was only indicated in the first two years of the series, 13% (20 patients) during hospitalization for the base disease and only 4% (6 patients) were specifically admitted for surgical preparation (plasma, platelets, and others). SVR were used for chemotherapy (124 cases, 82%), repeated transfusions (6 cases, 4%) and chronic medication (acquired immunodeficiency syndrome, infections) (30 patients, 20%). Forty-two percent permitted chemotherapy administration by continual transfusion on an out patient regime. RESULTS: A series of mechanical complications (3 cases, 2%), septic (9 episodes in 7 patients, 5%) and thrombotic (8 of the catheter) (5%) and 4 of the central veins (2%) were observed. In the present series the rate of infections (5%) (0.072 episodes of bacteremia per 100 days/patient) and thrombosis (3%) was very low due to a strict protocol of maintenance and control by the medical team and hospital staff. The need for radiologic control during surgery is emphasized although, as demonstrated in the present review, the technique of localization by a cath-finder (external detector) permits greater speed with the same security. CONCLUSIONS: The degree of patient satisfaction and the minimum incidence of serious complications in determined risk groups (neutropenia, acquired immunodeficiency syndrome) demonstrates that subcutaneous venous reservoirs (SVR) constitute an excellent method as a chronic venous access. The SVR present a lower rate of complications if compared with any historic series of external vascular catheterization.


Subject(s)
Acquired Immunodeficiency Syndrome/drug therapy , Catheters, Indwelling , Hematologic Diseases/drug therapy , Neoplasms/drug therapy , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Vascular Surgical Procedures/methods , Veins
SELECTION OF CITATIONS
SEARCH DETAIL
...