Subject(s)
Adolescent Health Services , Adolescent Medicine , Adolescent , Adolescent Behavior , HumansSubject(s)
Health Education/methods , Information Services/organization & administration , Journalism, Medical/standards , Societies, Medical/organization & administration , Adolescent , Adolescent Medicine/organization & administration , Female , Humans , Leadership , Male , Peer Review , United StatesSubject(s)
Adolescent Health Services , Adolescent Medicine , Psychology, Adolescent , Adolescent , HumansSubject(s)
Hepatitis B Vaccines/administration & dosage , Hepatitis B/prevention & control , Acute Disease , Adolescent , Adolescent Health Services/organization & administration , Child , Chronic Disease , Hepatitis B/epidemiology , Hepatitis B/transmission , Humans , Mass Screening , Prevalence , School Health Services/organization & administration , United States/epidemiology , Vaccination/methodsABSTRACT
Two enzyme immunoassays (EIAs) detecting Chlamydia trachomatis from endocervical swabs, Syva MicroTrak (MT) and Abbott Chlamydiazyme (CZ), were compared with a tissue culture (TC) standard. Initially, 8% (100 of 1250) of specimens were TC positive, yielding sensitivities of 94% (94 of 100) for MT and 79% (79 of 100) for CZ with identical 98% specificities (1129 of 1150 for MT and 1130 of 1150 for CZ). Discrepant specimens were retested by both EIAs and assayed for elementary bodies (EBs) by a fluorescent antibody test. After discrepancy analysis, 9.5% (118) of 1240 patients were either TC or EB positive, yielding sensitivities of 94.1% for MT (111 of 118) and 79.7% for CZ (94 of 118) with identical specificities of 100% (1122 of 1122). These results indicate that the MT is significantly more sensitive (p less than 0.05, McNemar test) than CZ in detecting C. trachomatis from endocervical swabs.
