1.
Chemistry
; 20(42): 13527-30, 2014 Oct 13.
Article
in English
| MEDLINE
| ID: mdl-25168197
ABSTRACT
Here we demonstrate that deracemization of isoindolinones using Viedma ripening is possible starting from a racemic mixture of conglomerate crystals. Crystals of the enantiopure isoindolinones lose their chiral identity upon dissolution even without the need for a catalyst. This enabled complete deracemization of the reported isoindolinones without a catalyst.