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Kosm Biol Aviakosm Med ; 16(6): 34-7, 1982.
Article in Russian | MEDLINE | ID: mdl-6294407

ABSTRACT

The respiration of mitochondria isolated from mixed skeletal muscles of hindlimbs of rats flown for 18.5 days on Cosmos-936 was investigated polarographically. At R + 10 hours the rate of mitochondrial respiration in different metabolic states during the oxidation of succinic acid and NAD-dependent substrates declined. The enzyme activity of mitochondrial cytochrome oxidase and cytosol lactate dehydrogenase diminished. At R + 25 days both aerobic and anaerobic oxidative processes increased, thus leading to the recovery of the parameters (sometimes they not only returned to the norm but exceeded it).


Subject(s)
Energy Metabolism , Muscles/enzymology , Space Flight , Animals , Electron Transport Complex IV/metabolism , L-Lactate Dehydrogenase/metabolism , Oxidation-Reduction , Rats , Time Factors , USSR
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