Subject(s)
Coronavirus Infections/complications , Coronavirus Infections/diagnostic imaging , Lung Injury/complications , Lung Injury/diagnostic imaging , Pneumonia, Viral/complications , Pneumonia, Viral/diagnostic imaging , Tomography, X-Ray Computed/methods , Aged , Belgium , Betacoronavirus , COVID-19 , Female , Humans , Lung/diagnostic imaging , Male , Middle Aged , Pandemics , SARS-CoV-2 , Sex FactorsABSTRACT
OBJECTIVE: To study the diagnostic efficacy of endometrial cytology with the Abradul cell sampler and the effect of supplementing it, in cases with overly thick smears, with laser scanning confocal microscopy. STUDY DESIGN: Sampling was performed in 1,684 women. All patients underwent subsequent histology. In eight cases with overly thick smears the original smears were restained to allow confocal microscopy. RESULTS: Efficacy was high, with 1,593 good samples. Thirty-one endometrial carcinomas were signed out as cytologically positive and 10 as atypia. In addition, 10 squamous cell carcinomas of the cervix and 1 ovarian carcinoma were diagnosed with this method. Only one case (endocervical adenocarcinoma) was not detected in the sample. In the eight cases in which confocal microscopy was performed, the images were high quality, allowing a correct diagnosis. In addition, the transition from hyperplasia to carcinoma could be visualized in the cytologic smear. CONCLUSION: Endometrial cytology in an outpatient setting is highly effective, and confocal microscopy in selected cases is not only helpful but also highly instructive.
Subject(s)
Endometrial Neoplasms/pathology , Endometrium/pathology , Ovarian Neoplasms/pathology , Uterine Cervical Neoplasms/pathology , Vaginal Smears/instrumentation , Disposable Equipment , Endometrial Neoplasms/classification , Female , Humans , Microscopy, Confocal , Ovarian Neoplasms/classification , Uterine Cervical Neoplasms/classification , Vaginal Smears/methodsABSTRACT
BACKGROUND: Primary in situ fallopian tube carcinomas are rarely diagnosed, and malignant cells from this lesion have not been previously described as occurring in endometrial smears. CASE: A 57-year-old, postmenopausal woman had an endometrial smear that revealed adenocarcinoma cells associated with psammoma bodies. She also had smooth muscle cells in the smear compatible with uterine leiomyomas. Examination of the hysterectomy specimen disclosed a primary in situ carcinoma of the left fallopian tube and uterine leiomyomatosis. CONCLUSION: Endometrial cytology plays an important role in the diagnosis of pathologic processes in the uterus. It may also contribute useful information on extrauterine diseases.
