ABSTRACT
Clinical and microbiological study of wound discharge from 35 patients demonstrated a relationship between biological properties of S. aureus, the causative agent of burn infection, and the course of the infected burn trauma. The prognostic importance of the antioxidant properties of these staphylococci was established: in cases of the unfavorable course of the burn process they showed essentially greater resistance to peroxinitrite and higher superoxide dismutase activity in comparison with the cultures isolated from patients with uncomplicated wound infection.
Subject(s)
Burns/microbiology , Peroxynitrous Acid/pharmacology , Staphylococcal Infections/microbiology , Staphylococcus aureus/pathogenicity , Wound Infection/microbiology , Adult , Drug Resistance, Bacterial , Humans , Male , Middle Aged , Prognosis , Staphylococcal Infections/diagnosis , Staphylococcus aureus/drug effects , Staphylococcus aureus/isolation & purification , Superoxide Dismutase/metabolism , Wound Infection/diagnosisABSTRACT
Bacillus cereus production strain IP 5832 of the preparation "Bactisubtil" has been characterized with respect to its anticomplementary activity (ACA) and the parameters of its heterogeneity in the process of adaptation to trypticase-soybean medium and during cultivation in anaerobic conditions have been determined. The cultivation of B.cereus strain IP 5832 jointly with Escherichia coli, Enterobacter cloacae and Klebsiella pneumoniae strains, isolated in enteric disbiosis, affects ACA in different ways, which leads to structural changes in the populations of these enterobacteria, characterized by an increase of their heterogeneity with respect to ACA.
