ABSTRACT
Léon Monsel was born on March 13, 1816 in Gironde. He did training courses in chemist's first near of home and then in Paris. He also studied pharmacy in Pharmacy School of Paris where he succeeded on August 12, 1840 and he entered army. He remained in it until his retirement in 1874. He died at Nancy on April 15, 1878. Monsel is overall well known by his publications about coagulation power of ferric sub-sulfate from which he described three preparation ways. Current publications are exclusively foreigner. They point out advantages and disadvantages of Monsel's solution. It is used to day as hemostatic agent in minor surgical procedures such as biopsies in genecology, dermatology, proctology and O.R.L. Besides when he was stationed in Roma he studied Acqua Acetosa (acid salty gaseous water) of this town and later when he was stationed in Bordeaux, he took out a patent about manufacturing varnish from metallic resinates.
Subject(s)
Ferric Compounds/history , Hemostatics/history , History of Pharmacy , Sulfates/history , Chemistry/history , Ferric Compounds/pharmacology , France , History, 19th Century , Humans , Sulfates/pharmacology , Surgical Procedures, OperativeABSTRACT
OBJECTIVES: To evaluate the long-term results after Vecchietti's operation. STUDY DESIGN: Twenty Mayer-Rokitanski-Kuster-Hauser (MRKH) syndrome patients underwent creation of a neovagina using Vecchietti's operation by laparotomy (17 cases) and laparoscopy (3 cases). RESULTS: The mean age of the patients was 21 years (16-34). After 66 months (24-156) of follow-up, the mean length x diameter of the neovagina was 8.2 cm x 2.8 cm. The neovaginal epithelium was macroscopically similar to normal vaginal mucosa, except for one patient who had subsequently undergone insertion of skin graft. Post-operative sexual behavior revealed sexual desire and pleasure (100%), lubrication (94%), clitoral orgasm (87%) and vaginal-mediated orgasm (69%). Finally, 16 patients out of 18 (89%) were completely satisfied with the results of the operation. CONCLUSION: Vecchietti's operation may be suggested as one of the choice of treatments to correct vaginal aplasia in young MRKH syndrome patients.
