Subject(s)
Electrocardiography , Sleep/physiology , Adult , Aged , Coronary Disease/physiopathology , Female , Humans , Male , Middle AgedABSTRACT
302 patients after acute myocardial infarction were followed up. The average age was 52.28 years, the average time elapsed since discharge from hospital to the first examination by an exercise test was 45.35 days. 141 patients went through an out-patients' rehabilitation programme, 161 patients abstained from rehabilitation. The initial values of both groups of patients were identical. On the basis of a two and three-year observation the authors conclude that a low tolerance of physical load and heart volume above 790 ml are among the factors worsening the long-term prognosis of patients after myocardial infarction. The lower mortality of rehabilitated patients is certainly the result of all components of more intensive therapeutic care, surveillance and health education.
Subject(s)
Myocardial Infarction/diagnosis , Follow-Up Studies , Heart Function Tests , Humans , Middle Aged , Myocardial Infarction/pathology , Myocardial Infarction/rehabilitation , Myocardium/pathology , Physical Exertion , PrognosisSubject(s)
Hypertension/blood , Hypertension/urine , Norepinephrine/blood , Norepinephrine/urine , Physical Fitness , Epinephrine/urine , Female , Humans , Male , Middle AgedSubject(s)
Cardiomegaly/physiopathology , Coronary Circulation , Hemodynamics , Animals , Cardiomegaly/etiology , Heart Ventricles/physiopathology , Hypoxia , Rats , SwimmingABSTRACT
Total hemodynamic values and left ventricular blood flow were studied using Sapirstein's method of 86Rb uptake in female rats 24 h after a last exposure to high altitude. A stimulated altitude of 1350 m was used, initial exposure being for 30 min, gradually increased by 30 min daily up to 330 min daily for 5 days a week; the total number of exposures was 32. In another animal group the hypobaric exposure was combined with swimming in water at 37 degrees C. In both experimental groups the cardiac output and stroke volume increased, and in rats undergoing swimming the total peripheral resistance decreased as well. In the rats exposed to intermittent hypoxia only, left ventricular blood flow increased by about the same proportion as the cardiac output. The ratio of left ventricular work to coronary blood flow was significantly increased. In rats exposed to the combined influence of hypoxia and swimming, the increase in left ventricular blood flow did not match either the increase in cardiac output, or the weight gain of the left ventricle. The ventricular work to coronary blood flow ratio was the same as in controls.
