Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 4 de 4
Filter
1.
Ultrasound Obstet Gynecol ; 51(3): 323-330, 2018 Mar.
Article in English | MEDLINE | ID: mdl-28603940

ABSTRACT

OBJECTIVES: The main aim of this systematic review was to evaluate the prevalence and type of associated anomalies in fetuses with heterotaxy diagnosed prenatally on ultrasound; the perinatal outcome of these fetuses was also studied. METHODS: An electronic search of MEDLINE, EMBASE and CINAHL databases was performed. Only studies reporting the prenatal diagnosis of isomerism were included. Outcomes observed included associated cardiac and extracardiac anomalies, fetal arrhythmia, abnormal karyotype, type of surgical repair and perinatal mortality. The analysis was stratified according to the type of heterotaxy syndrome (left (LAI) or right (RAI) atrial isomerism). Meta-analyses of proportions were used to combine data. Quality assessment of the included studies was performed using the Newcastle-Ottawa Scale for cohort studies. RESULTS: Sixteen studies (647 fetuses) were included in the analysis. Atrioventricular septal defect was the most common associated major cardiac anomaly found both in fetuses with LAI (pooled proportion (PP), 59.3% (95% CI, 44.0-73.7%)), with obstructive lesions of the right outflow tract occurring in 35.5% of these cases, and in fetuses with RAI (PP, 72.9% (95% CI, 60.4-83.7%)). Fetal arrhythmias occurred in 36.7% (95% CI, 26.9-47.2%) of cases with LAI and were mainly represented by complete atrioventricular block, while this finding was uncommon in cases with RAI (PP, 1.3% (95% CI, 0.2-3.2%)). Abnormal stomach and liver position were found, respectively, in 59.4% (95% CI, 38.1-79.0%) and 32.5% (95% CI, 11.9-57.6%) of cases with LAI, and in 54.5% (95% CI, 38.5-70.1%) and 45.9% (95% CI, 11.3-83.0%) of cases with RAI, while intestinal malrotation was detected in 14.2% (95% CI, 2.5-33.1%) of LAI and 27.1% (95% CI, 7.9-52.0%) of RAI cases. Hydrops developed in 11.8% (95% CI, 2.9-25.6%) of fetuses diagnosed prenatally with LAI. Biventricular repair was accomplished in 78.2% (95% CI, 64.3-89.4%) of cases with LAI, while univentricular repair or palliation was needed in 17.0% (95% CI, 9.7-25.9%); death during or after surgery occurred in 26.8% (95% CI, 4.6-58.7%) of LAI cases. Most children with RAI had univentricular repair and 27.8% (95% CI, 15.5-42.1%) died during or after surgery. CONCLUSIONS: Fetal heterotaxy is associated with a high prevalence of cardiac and extracardiac anomalies. Approximately one quarter of fetuses with heterotaxy died during or after surgery. Abnormal heart rhythm, especially heart block, is common in fetuses with LAI, while this finding is uncommon in RAI. Biventricular repair was common in LAI while univentricular repair was required in the majority of children affected by RAI. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.


Subject(s)
Heart Septal Defects, Ventricular/diagnostic imaging , Heterotaxy Syndrome/diagnostic imaging , Prenatal Diagnosis , Ultrasonography, Prenatal , Vascular Surgical Procedures , Female , Heart Septal Defects, Ventricular/mortality , Heart Septal Defects, Ventricular/surgery , Heterotaxy Syndrome/mortality , Heterotaxy Syndrome/surgery , Humans , Infant, Newborn , Perinatal Death , Pregnancy , Survival Rate , Treatment Outcome
2.
Clin Exp Obstet Gynecol ; 44(1): 148-150, 2017.
Article in English | MEDLINE | ID: mdl-29714887

ABSTRACT

Endometriosis is an uncommon disease in postmenopausal women (PMW), ranging from 2% to 5% of cases, and it is very important to exclude neoplastic transformation of the endometrium. The authors would like to introduce the case of a 63-year-old overweight patient with abdominal pain associated to pain and swelling of the left inferior limb occurring for approximately six weeks. The CT X-ray of the abdomen revealed the presence of a retroperitoneal mass causing deep vein thrombosis because of extrinsic compression of the left iliac vein. Following removal of the pelvic masses with laparotomy, the histological exam revealed an endometriosis. The CT X-ray carried out after a month postoperatively revealed the root canal treatment of the left femoral vein with a considerable decrease of the thrombosis of homolateral external iliac veins. Despite the endometriosis, it is uncommon in women who have reached menopause and must be considered in the differential diagnosis of pelvic masses.


Subject(s)
Endometriosis/complications , Postmenopause , Retroperitoneal Space/surgery , Venous Thrombosis/etiology , Endometriosis/surgery , Female , Humans , Middle Aged , Overweight , Venous Thrombosis/diagnostic imaging , Venous Thrombosis/surgery
SELECTION OF CITATIONS
SEARCH DETAIL
...