Subject(s)
Adenoma, Pleomorphic/pathology , Eye Neoplasms/pathology , Lacrimal Apparatus/pathology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Adenoma, Pleomorphic/etiology , Adenoma, Pleomorphic/surgery , Adolescent , Antibiotics, Antineoplastic/adverse effects , Cyclophosphamide/adverse effects , Doxorubicin/adverse effects , Eye Neoplasms/etiology , Eye Neoplasms/surgery , Female , Humans , Immunosuppressive Agents/adverse effects , Methotrexate/adverse effects , Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Precursor Cell Lymphoblastic Leukemia-Lymphoma/radiotherapySubject(s)
Iris/blood supply , Retina/pathology , Cholesterol/blood , Color , Humans , Hypertriglyceridemia/complications , Infant, Newborn , MaleABSTRACT
INTRODUCTION: Over the last decades, various methods have been investigated for preschool screening for amblyogenic ametropia. The SureSight is a new hand-held wavefront-analyzing autorefractor designed for screening. METHODS: A total of 338 children (3 1/2 - 4 1/2 years-old) were examined in their kindergartens without cycloplegia using the new instrument. Of these, 56 had a cycloplegic retinoscopy as a reference measurement. Hyperopia > or =3 dpt, myopia > or =1 dpt, astigmatism > or =1 dpt and anisometropia > or =1 dpt were considered amblyogenic ametropia. RESULTS: Testability was 99.4%. Accuracy was high for cylinder power and axis but poor for the spherical equivalent. Sensitivity was 41% for the detection of amblyogenic hyperopia, 95% for astigmatism and 75% for anisometropia, with specificity values of 92, 79 and 73%. CONCLUSION: The high testability and accuracy for cylinder power and axis are the strong points. The poor accuracy for the spherical equivalent is probably caused by the lack of cycloplegia. At present, non-cycloplegic autorefractor screening cannot be recommended due to the low specificity. Our findings support the advice that objective refraction in childhood must be performed with cycloplegia.
