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1.
Virologie ; 37(3): 175-9, 1986.
Article in English | MEDLINE | ID: mdl-3020778

ABSTRACT

A spin-labelled derivative of amantadine was prepared and added to mouse liver and lung homogenates in vitro in the presence and in the absence of inhibitors of oxidative enzymes; the kinetics of the quenching of ESR signals was followed up in different experimental variants.


Subject(s)
Amantadine/metabolism , Liver/metabolism , Lung/metabolism , Animals , Azides/pharmacology , Electron Spin Resonance Spectroscopy , In Vitro Techniques , Kinetics , Mice , Oxidation-Reduction/drug effects , Potassium Cyanide/pharmacology , Sodium Azide
4.
Physiologie ; 16(1): 71-5, 1979.
Article in English | MEDLINE | ID: mdl-106418

ABSTRACT

Studies on liver homogenates obtained from Wistar rats revealed that the ageing process produces the loss of glucose-6-phosphate dehydrogenase activity and higher values in the thermolabile fraction of this enzyme. The biotrophic treatment with Gerovital H3 has a strong influence upon glucose-6-phosphate dehydrogenase with tendency to diminish the thermolabile fractions.


Subject(s)
Glucosephosphate Dehydrogenase/metabolism , Liver/enzymology , Procaine/pharmacology , Age Factors , Animals , Liver/drug effects , Rats
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