[Cancer of the cervix uteri in young people]. / Cancerul colului uterin la tinere.

The age-group distribution, risk factors, histopathological aspects, diagnosis, treatment and prognosis of 111 diagnosed and/or treated cervical carcinomas in women aged up to 40 years out of 478 cases with the same diagnosis were reviewed. It is considered that the incidence of 23.2% in this series is situated at the extreme of the high frequencies reported in the literature. Nineteen per cent of the cases were diagnosed in stages O and Ia, a well organize program for early detection being required. In our series, the 5-year survival rate was 73.3%. This finding, although in a small series of cases, supports the opinion that age has no influence upon the prognosis of this disease.

[Endometrial carcinoma in cases under 45 years of age]. / Carcinomul endometrial la cazuri cu vîrste sub 45 ani.

Twelve cases of endometrial carcinoma admitted to the I-st Clinic of Obstetrics and Gynecology of Iasi in the interval 1983-1988 are presented. The patients' age ranged between 33 years (1 case) and 45 years (1 case) with a mean age of 41.3 years. This study was underwent given the increased frequency of this lesion in the premenopausal women (9.3% of all cases recorded in the interval under study). The incidence of the disturbed menstrual cycle was of 58%, that of obstetrical antecedents and obesity of 33% and 50%, respectively. In two cases there was a carcinoma "in situ", the remainder of cases presenting disease in stage I (FIGO classification). The diagnosis was made preoperatively in 7 cases, the other 5 patients being operated upon for uterine fibromatosis. Adenocarcinoma was the most common histological type. The need of ascertaining the etiology of metrorrhagias no matter of patients' age and the role of risk factors and some methods of detection (endometrial cytology, endometrial biopsy) are underlined.