[Thyroid functional activity in an experiment upon exposure to manganeferous dust].

The purpose of the study was to examine the effect of polymetallic manganeferous dust on thyroid function in an experiment. Biochemical and cytological studies were used. Seventy-day exposure caused decreased thyroid hormonal levels and thyroid cellular composition changes, which suggest that the dust in question has a cytotoxic effect. A prolonged (3-month) exposure provided evidence that suggests the tension of adaptive mechanisms in the thyroid system under the influence of a toxic factor. Nitric oxide was found to take an active part in the formation of adaptive mechanisms in thyroid tissue.

[Biochemical and hormonal characteristics of workers engaged into mining manganese-containing ores]. / Osobennosti biokhimicheskogo i gormonal'nogo statusa u rabochikh v usloviiakh otkrytoi dobychi marganetssoderzhashchei rudy.

Medical examination of workers engaged into digging of manganous ores proved correlation between nitrogen oxide level in expired air and rhinocytogram parameters, revealed sensitivity of cardiovascular and neuroendocrine systems to polymetallic dust.