1.
J Clin Pharm Ther
; 42(4): 499-501, 2017 Aug.
Article
in English
| MEDLINE
| ID: mdl-28417476
ABSTRACT
WHAT IS KNOWN AND THE OBJECTIVE: Acute generalized exanthematous pustulosis (AGEP) is a rare, severe cutaneous reaction that usually occurs following medication exposure. Clindamycin has rarely been linked to dermatologic side effects, including AGEP. CASE SUMMARY: This report details the case of a patient who developed AGEP with vancomycin and clindamycin use. After discontinuing clindamycin, the rash improved significantly. WHAT IS NEW AND CONCLUSION: Timely management of adverse skin reactions to antibiotics is paramount, and early identification of the culprit agent can allow for an alternative agent to be utilized. Clindamycin should be considered a potential causative agent for patients with skin reactions.