[Evaluation of potential damage to the regenerate during callus molding after mandibular distraction osteogenesis. Experimental study using an animal model]. / Evaluation der potenziellen Regeneratschädigung bei der Kallusumformung nach Distraktionsosteogenese der Mandibula. Eine experimentelle Untersuchung am Tiermodell.

BACKGROUND: Molding the regenerate created by distraction osteogenesis has clinically been shown to be an efficient lifeboat, good enough that for complex three-dimensional deformities final adjustments by molding the regenerate may be part of the treatment plan. The study assessed the limits of molding a regenerate, taking into consideration compressive and tensile forces acting simultaneously on the fresh callus. MATERIAL AND METHODS: Distraction osteogenesis was performed in 15 beagle mandibles using custom-made devices which allowed for lengthening as well as for angulation. After linear distraction of 10 mm, a defined 20 degrees angulation was performed in one acute step. The position of the fulcrum of the device allowed the regenerate to be compressed and stretched simultaneously. The effects on bone healing were assessed after 6 or 13 weeks of consolidation and compared to a control group where only linear distraction was performed. RESULTS: Radiological and histological investigations demonstrated that no significant difference between the biological behavior of the compressed and the stretched zone of the regenerate could be found. However, there were signs, showing the more critical character of the stretched area. After 6 weeks of consolidation, some specimens revealed delayed ossification of the stretched zone. Under stable conditions, this delay was compensated after 13 weeks of consolidation and complete osseous healing occurred. CONCLUSIONS: Under stable conditions, a fresh regenerate can be molded to a considerable extent without endangering osseous healing permanently. Nevertheless, tensile forces acting on the regenerate should be minimized to prevent damage to the new bone. This can be achieved by overdistraction prior to callus molding or by gradually changing the vector of distraction during the lengthening process.

Stressful life events and physical abuse among pregnant women in North Carolina.

OBJECTIVES: This study estimates the prevalence of stressful life events and physical abuse among North Carolina women prior to infant delivery, and examines potential associations between abuse and the other stressors. METHODS: Data were from the North Carolina Pregnancy Risk Assessment Monitoring System, a statewide representative survey of over 2,600 postpartum women. The survey assessed women's sociodemographic characteristics and their experiences of physical abuse and 13 other stressful life events before delivery. The prevalences of each life event and abuse were estimated. Logistic regression modeled the probability of women having high levels of stressful life events in relation to physical abuse and sociodemographics. RESULTS: Most women were married, white, high school graduates, aged 20 or older. The most common stressful life events were residential moves, increased arguing with husbands/partners, family member hospitalizations, financial hardship, and deaths of loved ones. Fourteen percent of women had high levels of stressful events (5 or more), and almost 9% were physically abused. Abuse was positively associated with increased arguing with husbands/partners, physical fighting, having someone close with an alcohol/drug problem, becoming separated/divorced, and financial hardship. Logistic regression analysis showed that a high level of stressful life events was significantly more likely among women abused both before and during pregnancy (OR = 11.94) and among women abused before but not during pregnancy (OR = 14.19). CONCLUSIONS: The high frequency of multiple stressful events and abuse in women's lives suggests that women's care providers should ask their patients about these issues, and offer appropriate referral/interventions to those in need.

Physical abuse of women before, during, and after pregnancy.

CONTEXT: Clinicians who care for new mothers and infants need information concerning postpartum physical abuse of women as a foundation on which to develop appropriate clinical screening and intervention procedures. However, no previous population-based studies have been conducted of postpartum physical abuse. OBJECTIVES: To examine patterns of physical abuse before, during, and after pregnancy in a representative statewide sample of North Carolina women. DESIGN, SETTING, AND PARTICIPANTS: Survey of participants in the North Carolina Pregnancy Risk Assessment Monitoring System (NC PRAMS). Of the 3542 women invited to participate in NC PRAMS between July 1, 1997, and December 31, 1998, 75% (n = 2648) responded. MAIN OUTCOME MEASURES: Prevalence of physical abuse during the 12 months before pregnancy, during pregnancy, and after infant delivery; injuries and medical interventions resulting from postpartum abuse; and patterns of abuse over time in relation to sociodemographic characteristics and use of well-baby care. RESULTS: The prevalence of abuse before pregnancy was 6.9% (95% confidence interval [CI], 5.6%-8.2%) compared with 6.1% (95% CI, 4.8%-7.4%) during pregnancy and 3.2% (95% CI, 2.3%-4.1%) during a mean postpartum period of 3.6 months. Abuse during a previous period was strongly predictive of later abuse. Most women who were abused after pregnancy (77%) were injured, but only 23% received medical treatment for their injuries. Virtually all abused and nonabused women used well-baby care; private physicians were the most common source of care. The mean number of well-baby care visits did not differ significantly by maternal patterns of abuse. CONCLUSION: Since well-baby care use is similar for abused and nonabused mothers, pediatric practices may be important settings for screening women for violence.

Who gets screened during pregnancy for partner violence?

CONTEXT: Despite recommendations to screen prenatal care patients for partner violence, the prevalence of such screening is unknown. OBJECTIVES: To estimate the statewide prevalence of partner violence screening during prenatal care among a representative sample of North Carolina women with newborns and to compare women screened for partner violence with women not screened. DESIGN, SETTING, AND PARTICIPANTS: This investigation examines data gathered through the North Carolina Pregnancy Risk Assessment Monitoring System, a random sample of more than 2600 recently postpartum women who were delivered of newborns between July 1997 and December 1998. MAIN OUTCOME MEASURES: Self-reports of violence, health service factors, and sociodemographic characteristics. ANALYSIS: The prevalence of screening was computed, and odds ratios and 95% confidence intervals were used to examine bivariate and multivariable associations between being screened for partner violence and other factors. RESULTS: Thirty-seven percent of women reported being screened for partner violence during prenatal care. Logistic regression analysis found that women were more likely to be screened if they received prenatal care from (1) a public provider paid by a public source; (2) a private provider paid by a public source; or (3) a public provider paid by a private source. CONCLUSIONS: These findings suggest that the majority of prenatal care patients in North Carolina are not screened for partner violence. Screening appears to be most highly associated with whether a woman is a patient in the public sector or the private sector, and with the source of payment for prenatal care. Arch Fam Med. 2000;9:1093-1099

Method of linking Medicaid records to birth certificates may affect infant outcome statistics.

OBJECTIVES: This study assessed how different methods of matching Medicaid records to birth certificates affect Medicaid infant outcome statistics. METHODS: Claims paid by Medicaid for hospitalization of the newborn and for the mother's delivery were matched separately to 1995 North Carolina live birth certificates. RESULTS: Infant mortality and low-birthweight rates were consistently lower when Medicaid was defined by a matching newborn hospitalization record than when results were based on a matching Medicaid delivery record. CONCLUSIONS: Studies of birth outcomes in the Medicaid population may have variable results depending on the method of matching that is used to identify Medicaid births.

Using Medicaid data to estimate state- and county-level prevalence of asthma among low-income children.

OBJECTIVES: Asthma is one of the most common illnesses among children, yet there is little reliable information on the number of children at the state and county level who are living with asthma. This study examines the prevalence of asthma among low-income children in North Carolina using Medicaid paid claims and enrollment data. METHODS: Claims paid by Medicaid during state fiscal year 1997-1998 with a diagnosis of asthma or for a prescription drug used to treat asthma are examined to estimate prevalence among children ages 0-14 years. Percentages of enrolled children with asthma are presented by age, race, and rural/urban residence, and the costs of asthma treatment are calculated. RESULTS: More than 12% of North Carolina children ages 0-14 years on Medicaid had an indication of asthma. Prevalence rates were found to be highest among younger children, some minority groups, and residents of rural areas. More than $23 million was paid by Medicaid during the fiscal year for asthma-related services for children ages 0-14 years. CONCLUSIONS: State Medicaid databases are a useful means of studying the prevalence of asthma and other health conditions in low-income populations. Strengths and weaknesses of the proposed methodology are discussed. Existing administrative data systems can provide quick updates of prevalence rates at the state and county level, enhancing the ability to study trends in illness over time.

Multiple deliveries in North Carolina: effects on birth outcomes.

OBJECTIVES: The purpose of this study is to examine the trends in multiple deliveries in North Carolina and assess their effect on the rates of low birth weight, fetal mortality, and infant mortality. METHODS: Using North Carolina vital statistics files, trends in multiple births, categorized by race, maternal age, and birth weight, were examined for the period 1980-1997. A partitioning method was used to estimate the contribution of maternal age distribution and age-specific multiple birth rates to the overall increase in multiple births, and the contribution of the changing multiple birth rate to observed trends in low birth weight and fetal and infant mortality. RESULTS: Between 1980 and 1997, the state's multiple birth rate increased by 40%. Most of the increase was due to a rise in the age-specific multiple birth rates, rather than a shift in the maternal age distribution. The increase in the multiple birth rate accounted for a substantial proportion of the increase in low birth weight among Whites and Blacks. The rise in multiple births also hindered further declines in fetal and infant mortality during this time. CONCLUSIONS: Multiple births are an increasingly important contributor to perinatal outcomes, and warrant greater consideration in research aimed at evaluating trends in low birth weight and infant mortality.

State health department and university evaluation of North Carolina's Maternal Outreach Worker Program.

INTRODUCTION: The Maternal Outreach Worker (MOW) Program is a social support intervention using lay helpers to provide support, health education, and outreach to Medicaid eligible women at risk for poor pregnancy and parenting outcomes. State Health Department and University collaborators designed a two-pronged evaluation comprised of programwide and interview study components to assess the impact of the program on pregnancy outcomes, health behaviors, and infant health status. METHODS: Programwide evaluation data are based on 1992-1995 N.C. birth files for the original 24 participating counties and include 1,726 MOW participant births and 12,988 comparison births whose records were linked to birth files and met the study criteria. For the interview study 373 MOW participants and 332 comparison women were personally interviewed three times: during pregnancy, one month postpartum, and one year after delivery. RESULTS: Risk factors associated with poor pregnancy and parenting outcomes were greater among MOW participants than comparisons in both the programwide and intensive study components. Caucasian MOW participants had slightly higher rates of adequate prenatal care. African Americans were found to have less adequate prenatal care. Fewer than expected LBW and VLBW births were observed for African-American MOW participants. MOW Program participation did not affect the utilization of health and social services for infants. African Americans, regardless of whether they received MOW services, fared better than Caucasians in terms of having their pregnancy needs fulfilled. CONCLUSIONS: Findings show the need to further explore appropriate measures of maternity support program outcomes and indicate inconsistent program benefit among subpopulations.

Etiology of low-birthweight birth: a population-based study.

BACKGROUND: Preterm and low-birthweight births remain the major correlates of infant mortality in the United States. The recognition that these births result from varying proximal etiologies is essential to the development of preventive strategies specific to each etiologic group. METHODS: Using vital statistics data tapes provided by the North Carolina Center for Health and Environmental Statistics, mothers in 20 counties who delivered infants with birthweights between 1 pound and 5 pounds, 8 ounces were identified. Maternal hospital records of 4,754 women were reviewed for data about prenatal and intrapartal events. Two perinatologists classified births into four proximal etiology groups: term-lowbirthweight, medically indicated preterm birth, preterm premature rupture of membranes, and idiopathic preterm birth. Information from birth certificate and hospital records was merged to provide an expanded data set. RESULTS: Race, age, education, and marital status are associated with different patterns of proximal etiology. Rates were higher for all etiologies in black women and in young women; however, the absolute number of LBW births was highest among white women. Idiopathic preterm birth was highest in black women and decreased as age increased; medical indications for preterm birth increased with increasing age. CONCLUSIONS: Classification of LBW births by etiologic group provides insights of value to both clinicians and researchers. Studies in which LBW and/or preterm birth are the outcome variables will be enhanced by identifying etiology. Multiple preventive strategies should address varying etiologic groups.

Maternal mortality related to induced abortion in North Carolina: a historical study.

A study of trends in maternal mortality from 1963 to 1992 in North Carolina shows that during the period 1973-1977, when legal abortion first became available, the maternal mortality ratio (maternal deaths per 100,000 live births) for deaths related to induced abortion was almost 85% lower than the ratio during the previous five-year period. The decrease in abortion-related mortality had a substantial impact on the overall maternal mortality ratio during this period, accounting for about 46% of the total decline in maternal deaths. After 1977, the maternal mortality ratio for induced abortion declined to less than one death per 100,000 live births, while the mortality ratio for all other obstetric causes leveled off at about 10 deaths per 100,000 live births.

The quality of the new birth certificate data: a validation study in North Carolina.

A random sample of 395 December 1989 North Carolina birth certificates and the corresponding maternal hospital medical records were examined to validate selected items. Reporting was very accurate for birth-weight, Apgar score, and method of delivery; fair to good for tobacco use, prenatal care, weight gain during pregnancy, obstetrical procedures, and events of labor and delivery; and poor for medical history and alcohol use. This study suggests that many of the new birth certificate items will support valid aggregate analyses for maternal and child health research and evaluation.

Prenatal WIC participation can reduce low birth weight and newborn medical costs: a cost-benefit analysis of WIC participation in North Carolina.

A number of previous studies have found that prenatal participation in the Special Supplemental Food Program for Women, Infants, and Children (WIC) improves birth outcomes, but only a few studies have provided cost-benefit analyses. The present study linked Medicaid and WIC data files to birth certificates for live births in North Carolina in 1988. Women who received Medicaid benefits and prenatal WIC services had substantially lower rates of low and very low birth weight than did women who received Medicaid but not prenatal WIC. Among white women, the rate of low birth weight was 22% lower for WIC participants and the rate of very low birth weight was 44% lower; among black women, these rates were 31% and 57% lower, respectively, for the WIC participants. Multivariate logistic regression analysis confirmed that prenatal participation in a WIC program reduced the rate of low birth weight. It was estimated that for each $1.00 spent on WIC services, Medicaid savings in costs for newborn medical care were $2.91. A higher level of WIC participation was associated with better birth outcomes and lower costs. These results indicate that prenatal WIC participation can effectively reduce low birth weight and newborn medical care costs among infants born to women in poverty.

The effect of family planning participation on prenatal care use and low birth weight.

Data on approximately 45,000 North Carolina women who gave birth in 1989 and 1990 and received prenatal care in public health facilities were studied to assess the effects in a low-income population of prior family planning services on low birth weight and adequacy of prenatal care. Women who had used family planning services in the two years before conception were significantly more likely than those who had not used such services to have a birth-to-conception interval of greater than six months. They were also more likely to receive early and adequate prenatal care and to be involved in a food supplement program and maternity care coordination. In addition, the family planning participants were less likely than the nonparticipants to be younger than 18 and were somewhat less likely to deliver a low-birth-weight infant. Though the results of this retrospective study must be interpreted with caution because of such factors as self-selection into family planning programs, they suggest that family planning services may improve birth weight and use of prenatal health services among low-income women.

PIP: To determine the effects of prior use of family planning services on birth weight and adequacy of prenatal care, researchers compared data on 14,338 low-income women who gave birth in North Carolina during 1989-1990 and had earlier attended family planning services at public health clinics with data on 30,761 low-income women who also gave birth in 1989-1990 but did not use family planning services. Both groups of women basically matched in terms of education, Medicaid coverage, marital status, smoking history, medical risk factors, and previous incompleted pregnancy, or infant or child mortality. Most women who used family planning services were black (64% vs. 48.1%). 18-year old and younger women who used family planning services had fewer births than those who did not use family planning services (7.2% vs. 14.7% for whites and 9.6% vs. 19.7% for blacks; p .001). Further, women who used family planning services were more likely to participate in the food supplementation program referred to as WIC (89.9% vs. 86.6% for blacks and 87.9% vs. 81.7% for whites; p .001) and in the maternity care coordination program for Medicaid recipients (59.4% vs. 52.9% for blacks and 50.2% vs. 44.1% for whites; p .001). Moreover, they tended to receive earlier and more adequate prenatal care (51.6% receiving no are in 1st trimester vs. 58.3% receiving care in 1st trimester for blacks, and 40% vs. 47.1% for whites, and 51.6% vs. 58.3% for blacks and 40% vs. 47.1% for whites; p .001 respectively). They were also less likely to deliver a low birth weight (LBW) infant than those who did not use these services, but the difference was only significant for blacks (13.1% for no visits vs. 12.2% for any visit [p .05] and 11.6% for at least 3 visits [p .1]); for whites, 7.9% for no visits vs. 7.4% for any visit and at least 3 visits. Despite the possibility of self selection bias, these findings indicate that family planning services reduce the incidence of LBW and improve use of prenatal health services.