Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
J Phys Condens Matter ; 29(30): 30LT01, 2017 Aug 02.
Article in English | MEDLINE | ID: mdl-28574404

ABSTRACT

The three-dimensional topological insulator Bi2Se3 presents two cone-like dispersive topological surface states centered at the [Formula: see text] point. One of them is unoccupied in equilibrium conditions and located 1.8 eV above the other one lying close to the Fermi level. In this work we employ time- and angle-resolved photoemission spectroscopy with circularly polarized pump photons to selectively track the spin dynamics of the empty topological states. We observe that spin-polarized electrons flow along the topological cone and recombine towards the unpolarized bulk states on a timescale of few tens of femtoseconds. This provides direct evidence of the capability to trigger a spin current with circularly polarized light.

2.
Acta Neuropathol ; 97(2): 127-38, 1999 Feb.
Article in English | MEDLINE | ID: mdl-9928823

ABSTRACT

Canine X-linked muscular dystrophy (CXMD) is genetically homologous to Duchenne muscular dystrophy and shares the severe myopathy and lethal clinical development of the human disease. We used immunohistochemistry to characterize the time course of postnatal expression of adult fast, adult slow and developmental myosin in the muscle of CXMD dogs, carriers and healthy controls. We also characterized the expression of utrophin and dystrophin. This detailed immunolocalization study confirmed that postnatal muscle maturation is delayed in normal dogs compared to other animals and humans, and is only achieved at around 60 days. In CXMD dogs major derangement of myosin expression became evident from about 15 days; there was a selective loss of fibers expressing fast myosin and persistence of developmental fibers compared to controls. In carriers, the proportion of dystrophin-deficient fibers, which mainly expressed fast myosin, decreased with age. In controls and carriers utrophin was absent from muscle fiber surfaces in 2-day-old animals but present between 15 and 30 days, to mostly disappear by 60 days. In dystrophic animals, sarcolemmal expression of utrophin was more marked and persistent. That immature neonatal muscle from control dogs normally contains sarcolemmal utrophin may have implications for the success of utrophin up-regulation therapy to correct the dystrophic phenotype. The data of this study provide important baseline information for further studies on the development and progression of pathological changes in the muscle of CXMD dogs.


Subject(s)
Cytoskeletal Proteins/biosynthesis , Membrane Proteins/biosynthesis , Muscle Development , Muscle, Skeletal/growth & development , Muscle, Skeletal/metabolism , Muscular Dystrophy, Animal/metabolism , Myosin Heavy Chains/biosynthesis , Aging , Animals , Dogs , Female , Genetic Linkage , Heterozygote , Homozygote , Immunoblotting , Immunohistochemistry , Male , Muscular Dystrophy, Animal/genetics , Protein Isoforms/biosynthesis , Utrophin , X Chromosome/genetics
SELECTION OF CITATIONS
SEARCH DETAIL
...