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Thrombolysis in recurrent lacunar stroke: a case example.

Nguyen, T H; Vo, D; Ngo, M B; Truong, A L T; Bui, C Q; Nguyen, L K; Le, T V.

Eur J Neurol ; 15(12): 1409-11, 2008 Dec.

Article in English | MEDLINE | ID: mdl-19049563

ABSTRACT

BACKGROUND AND PURPOSE: We report a case of intravenous thrombolysis in a patient with early recurrent stroke. A 62-year-old man recovered nearly completely after a lacunar infarct of the left putamen. He suffered stroke recurrence 7 days later due to a new infarct in the left internal capsule. Intravenous alteplase 0.9 mg/kg was administered 40 min after the symptom onset resulting in significant neurologic improvement. CONCLUSION: Intravenous thrombolysis may be safe for early recurrent lacunar stroke in patients with relatively small risk of hemorrhage.

Subject(s)

Brain Infarction/drug therapy , Brain Ischemia/drug therapy , Internal Capsule/drug effects , Thrombolytic Therapy/methods , Tissue Plasminogen Activator/administration & dosage , Brain Infarction/pathology , Brain Infarction/physiopathology , Brain Ischemia/pathology , Brain Ischemia/physiopathology , Carotid Stenosis/diagnostic imaging , Carotid Stenosis/drug therapy , Carotid Stenosis/physiopathology , Disease Progression , Emergency Medical Services/methods , Emergency Medical Services/standards , Fibrinolytic Agents/administration & dosage , Humans , Internal Capsule/pathology , Magnetic Resonance Angiography , Magnetic Resonance Imaging , Male , Middle Aged , Middle Cerebral Artery/drug effects , Middle Cerebral Artery/pathology , Middle Cerebral Artery/physiopathology , Paresis/etiology , Paresis/physiopathology , Platelet Aggregation Inhibitors/pharmacology , Putamen/blood supply , Putamen/drug effects , Putamen/pathology , Secondary Prevention , Time Factors , Treatment Outcome , Ultrasonography

ABSTRACT

Subject(s)

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