Subject(s)
Acne Vulgaris/drug therapy , Evidence-Based Practice , Practice Guidelines as Topic , Europe , HumansABSTRACT
A female patient with coexistence of pemphigus herpetiformis and systemic lupus erythematosus is described. She presented to our Department with pruritic vesicles on her trunk and extremities, which were later accompanied with butterfly like erythema on her face and with central nervous system (CNS) manifestations. The diagnosis of pemphigus herpetiformis was based on the clinical picture and immunofluorescence finding, because the histopathologic finding is not always typical for the diagnosis. The diagnosis of systemic lupus erythematosus was based on positive ANA and anti-dsDNA, presence of butterfly-like erythema on her face, and CNS manifestations. The patient was treated by corticosteroids in combination with immunosuppressants, which should ensure good control of both diseases. The coexistence of pemphigus herpetiformis and systemic lupus erythematosus has not been reported in recent literature.
Subject(s)
Lupus Erythematosus, Systemic/diagnosis , Pemphigus/diagnosis , Abdomen , Adult , Diagnosis, Differential , Facial Dermatoses/complications , Facial Dermatoses/diagnosis , Facial Dermatoses/drug therapy , Facial Dermatoses/pathology , Female , Humans , Immunosuppressive Agents/therapeutic use , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/drug therapy , Lupus Erythematosus, Systemic/pathology , Pemphigus/complications , Pemphigus/drug therapy , Pemphigus/pathologyABSTRACT
A case of widespread tinea due to Trichophyton mentagrophytes is described. A healthy 75-year-old woman presented with 134 typical tinea corporis and faciei lesions previously treated with topical steroids. The diagnosis was based on direct mycologic examination and culture. The treatment with oral administration of terbinafine for four weeks and topical application of clotrimazole resulted in complete clinical resolution of the lesions
