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Eur J Ophthalmol ; 9(1): 8-13, 1999.
Article in English | MEDLINE | ID: mdl-10230586

ABSTRACT

PURPOSE: To reduce antigenicity of allografts and stimulate their replacement by natural recipient tissues. METHODS: Experimental allotransplantation of different tissues (fascias, tendons, derma, fat, etc.) with histological, histochemical, electron microscopical, electron histochemical examination 3, 5, 7, 14, 21, 30, 60, 120, 180 and 360 days postoperatively. RESULTS: Allografts of different tissues with glucosaminoglycans extracted from collagen fibers have low antigenicity and can be replaced by natural tissues. Allografts with these properties were named 'Alloplant'. CONCLUSIONS: Alloplant biomaterials can selectively stimulate natural tissue regeneration. Hence, Alloplant biomaterials can be utilized in surgery for the restoration of different tissues.


Subject(s)
Biocompatible Materials , Conjunctiva/surgery , Eyelids/surgery , Tissue Transplantation , Adipose Tissue/cytology , Adipose Tissue/metabolism , Adipose Tissue/transplantation , Adolescent , Adult , Animals , Conjunctiva/cytology , Eyelids/cytology , Fascia Lata/cytology , Fascia Lata/metabolism , Fascia Lata/transplantation , Glycosaminoglycans/metabolism , Glycosaminoglycans/ultrastructure , Humans , Isoantigens/metabolism , Middle Aged , Rabbits , Rats , Sclera/cytology , Sclera/metabolism , Sclera/transplantation , Tendons/cytology , Tendons/metabolism , Tendons/transplantation , Transplantation, Homologous
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