Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 6 de 6
Filter
1.
Int J Pediatr ; 2024: 3279878, 2024.
Article in English | MEDLINE | ID: mdl-38250570

ABSTRACT

Background: Congenital heart disease (CHD) remains the number one birth defect worldwide. Pulse oximetry screening (POS) is a widely used CHD screening modality effective in detecting critical lesions. This study is aimed at assessing the accuracy and cost-effectiveness of POS in a cohort of term well-babies admitted to a regular nursery in a tertiary care center. Methods: We reviewed the charts of term babies admitted to our regular nursery over a period of one year. The results of POS and the findings of echocardiography were collected. Similarly, we explored the records of our fetal echocardiography program to identify the fetuses screened for CHD during the same period. Results: 900 term babies were born and admitted to newborn nursery at our center, and 69 fetuses were evaluated by our fetal cardiology team during the study period. None of our term babies had a positive POS at birth or 24 hours of age. However, 56 babies had a cardiac echo before hospital discharge due to suspicious findings on physical examination or a family history of CHD. A simple noncritical CHD was noted in 10 of them. Additionally, 53 babies underwent echocardiography within the first five years of life; a simple CHD was noted in 6 of them. In parallel, 21 of our fetuses were found to have CHD: 16 simple CHD and 5 critical CHD (CCHD). Conclusion: Despite its cost-effectiveness and efficacy in screening for CCHD, POS is suboptimal for detecting simple CHD. In the absence of a proper prenatal screening and fetal echocardiography program, POS remains a cost-effective modality for detecting CCHD.

2.
Cardiol Young ; 32(1): 165-168, 2022 Jan.
Article in English | MEDLINE | ID: mdl-34134808

ABSTRACT

We herein report on a series of four patients presented to our tertiary care centre with features of multisystem inflammatory syndrome in children and cardiac involvement. Two of our patients had recent exposure to a COVID-19-positive patient, one had recent documented infection, and another had no known positive contact. All the patients were tested positive for severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibody at the time of presentation. All of them fulfilled the diagnostic criteria according to the World Health Organization Centers for Disease Control or the British guidelines for MIS-C (fever for ≥3 days, multisystem involvement (at least two), elevated markers of inflammation, and no other alternative diagnosis).Cardiac involvement was variable ranging from isolated ectasia of the coronary arteries to full-blown pancarditis such as severe biventricular dysfunction, multi-valvar involvement, and pericardial effusion.All our patients received intravenous immunoglobulin (2 g/kg), methylprednisolone, and aspirin and some required inotropic support and ICU admission.Remarkably, all our patients showed significant improvement in their cardiac disease within a few days as evident on serial echocardiographic evaluation. However, we stress the need for long-term follow-up as one of our patients demonstrated mild LV myocardial scarring as evident by gadolinium late enhancement on a cardiac MRI.


Subject(s)
COVID-19 , Pericardial Effusion , COVID-19/complications , Child , Humans , Pandemics , SARS-CoV-2 , Systemic Inflammatory Response Syndrome
3.
Ann Thorac Surg ; 85(1): 179-84, 2008 Jan.
Article in English | MEDLINE | ID: mdl-18154805

ABSTRACT

BACKGROUND: We sought to identify the prevalence of bicuspid pulmonary valve among patients with transposition of the great arteries undergoing the arterial switch operation and evaluate functional integrity of that valve in the neoaortic position. METHODS: Between October 1985 and December 2001, 391 patients had an arterial switch operation for transposition and its variants. Perioperative information and follow-up data were available for 342 patients. The serial echocardiograms of patients with bicuspid pulmonary valve were reviewed. The neoaortic valve was serially assessed, focusing on aortic insufficiency, annulus diameter, and pressure gradients. RESULTS: Twenty-four patients (7%) had a bicuspid pulmonary valve. Age at operation was 5 days to 12 years. Two patients were lost to follow up, and 22 patients had mean follow-up of 5.3 years (range, 2 months to 13 years), of which 21 patients were alive and 1 died late. At least two postoperative echocardiogram reports were available on 19 patients. Seven patients had no neoaortic regurgitation, and 10 had trivial regurgitation. Severe aortic regurgitation developed in 1 patient with endocarditis and in another with repair of Taussig-Bing anomaly. Neoaortic valve size indexed to body surface area showed an increase in annular diameter over time proportional to somatic growth. No significant valve stenosis developed. CONCLUSIONS: Encountering a bicuspid pulmonary valve at the time of an arterial switch operation is not uncommon. The integrity of a bicuspid pulmonary valve in the neoaortic position is maintained at a mean follow-up of 5.3 years. We believe that the presence of a bicuspid pulmonary valve is not a contraindication to an arterial switch operation.


Subject(s)
Aortic Valve Insufficiency/epidemiology , Cardiac Surgical Procedures/methods , Mitral Valve/abnormalities , Pulmonary Valve/abnormalities , Transposition of Great Vessels/surgery , Abnormalities, Multiple/diagnosis , Abnormalities, Multiple/epidemiology , Analysis of Variance , Aortic Valve Insufficiency/diagnostic imaging , Cardiac Surgical Procedures/adverse effects , Child , Child, Preschool , Cohort Studies , Echocardiography, Doppler , Female , Follow-Up Studies , Humans , Infant , Infant, Newborn , Male , Mitral Valve/diagnostic imaging , Prevalence , Probability , Pulmonary Valve/diagnostic imaging , Retrospective Studies , Risk Assessment , Survival Rate , Time Factors , Transposition of Great Vessels/diagnosis , Transposition of Great Vessels/mortality , Treatment Outcome
4.
Cardiol Young ; 13(1): 98-100, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12691294

ABSTRACT

We report two siblings with isolated ectopic hearts. Neither child had associated congenital diseases. To the best of our knowledge, this is the first reported familial occurrence of ectopic hearts.


Subject(s)
Cardiac Surgical Procedures/methods , Heart Defects, Congenital/diagnosis , Heart Defects, Congenital/surgery , Echocardiography, Doppler , Female , Follow-Up Studies , Humans , Infant, Newborn , Male , Radiography, Thoracic , Risk Assessment , Siblings , Treatment Outcome
6.
Asian Cardiovasc Thorac Ann ; 10(2): 129-32, 2002 Jun.
Article in English | MEDLINE | ID: mdl-12079935

ABSTRACT

We sought to determine if a higher dose of heparin would reduce arterial complications in patients weighing 10 kg or less undergoing cardiac catheterization to investigate congenital heart disease. Sixty patients were given either 100 (group A) or 150 (group B) IU x kg(-1) of heparin in a double-blinded randomized manner. Initial arterial access was established using a 4F cannula in all patients. Mean activated clotting time measured 20 minutes following heparin administration was significantly lower in group A than in group B (199 versus 251 seconds). Only 3 out of 60 patients (5%) required treatment for loss of femoral pulse. The age, weight, activated clotting time, length of catheterization procedure, time taken to establish arterial access, and the duration of arterial cannulation were comparable between the groups. Weight under 4 kg, age under 1 month, and cannula size larger than 4F were identified as independent risk factors for the development of arterial complications. Arterial access using a 4F cannula is a safe procedure in children weighing 10 kg or less. The incidence of significant arterial complications is low, and they do not appear to be preventable by a higher dose of heparin.


Subject(s)
Anticoagulants/administration & dosage , Cardiac Catheterization/adverse effects , Heart Defects, Congenital/diagnosis , Heparin/administration & dosage , Thrombosis/prevention & control , Anticoagulants/therapeutic use , Body Weight , Double-Blind Method , Heparin/therapeutic use , Humans , Infant , Logistic Models , Partial Thromboplastin Time , Risk Factors , Thrombosis/etiology
SELECTION OF CITATIONS
SEARCH DETAIL
...