1.
Biull Eksp Biol Med
; 106(11): 568-70, 1988 Nov.
Article
in Russian
| MEDLINE
| ID: mdl-3196857
ABSTRACT
In the experiments on rats the peptic ulcer of duodenum was simulated by means of mechanic compression of reflexogenic zones of pylorus and intestine. The destruction of duodenal mucosa was developed in 3-4 hours after the compression and retained in the course of 5-6 days. Piracetam (200 mg/kg) and etimizol (3 mg/kg) eliminated and cimetidine (25 mg/kg), solcoseryl (0.5 mg/kg) and metacine (5 mg/kg) diminished the destruction after the course of 6 injections of each drug with an interval of 10-12 hours. Therapeutic effects of piracetam and etimizol correlated with their ability to return towards normal concentration of creatine phosphate.
Subject(s)
Duodenal Ulcer/drug therapy , Psychotropic Drugs/therapeutic use , Animals , Disease Models, Animal , Drug Evaluation, Preclinical , Duodenal Ulcer/metabolism , Duodenum/drug effects , Duodenum/metabolism , Energy Metabolism/drug effects , Male , Phosphocreatine/metabolism , Rats , Time Factors
2.
Klin Med (Mosk)
; 65(10): 56-8, 1987 Oct.
Article
in Russian
| MEDLINE
| ID: mdl-3123768
Subject(s)
Central Nervous System Agents/therapeutic use , Hyperbaric Oxygenation , Peptic Ulcer/therapy , Acute Disease , Adult , Combined Modality Therapy , Etimizol/therapeutic use , Female , Humans , Male , Middle Aged , Oxyphenonium/therapeutic use , Parasympatholytics/therapeutic use , Piracetam/therapeutic use
3.
Klin Med (Mosk)
; 64(1): 99-101, 1986 Jan.
Article
in Russian
| MEDLINE
| ID: mdl-3959528
4.
Sov Med
; (12): 116-7, 1985.
Article
in Russian
| MEDLINE
| ID: mdl-3913004
5.
Sov Med
; (3): 70-2, 1985.
Article
in Russian
| MEDLINE
| ID: mdl-4023838