Subject(s)
Physician-Patient Relations , Bioethics , Humans , Physician-Patient Relations/ethics , South CarolinaABSTRACT
A hallmark of fetal growth restriction (FGR) is restricted placental development and insufficient nutrient supply to the fetus. It has previously been shown that activity levels of telomerase, the enzyme responsible for completing replication of telomeric DNA during cell division, is suppressed in FGR placenta samples as compared to control placenta samples from donors of the same gestational age. Here we examine whether telomere length maintenance is also compromised in FGR placenta samples. Southern analysis of telomere length for placenta and cord blood samples from 32 FGR and 36 control donors, ranging in gestational age from 37 to 40 weeks, revealed significantly shorter telomeres (PSubject(s)
Biomarkers
, Cellular Senescence/genetics
, Fetal Growth Retardation/genetics
, Telomere/physiology
, Adolescent
, Adult
, Biomarkers/metabolism
, Case-Control Studies
, Chromosomal Instability/physiology
, Female
, Fetal Growth Retardation/metabolism
, Humans
, Infant, Newborn
, Middle Aged
, Pregnancy
, Telomere/metabolism
, Up-Regulation/genetics
, Young Adult
ABSTRACT
Theft by employees costs American businesses and their customers many billions of dollars each year. Despite concerted efforts to reduce the problem, it appears to continue to grow. Most of these efforts concentrate on limiting the opportunity to steal. However, because the motivations for theft are varied, preventing it often requires more than tighter security. In this paper, the authors explore the extent of the problem, its causes, motivations behind employee theft, and some cost-effective ways of reducing the incidence of theft.
Subject(s)
Personnel Management/methods , Theft/prevention & control , Hospitals , Humans , United StatesABSTRACT
24 left movers, 24 right movers and 24 mixed movers, categorized on the basis of their conjugate lateral eye movements, were measured on latency of verbal response to arithmetic questions. The predicted superiority of right movers in speed of response did not occur nor did interference with habitual direction of conjugate lateral eye movement affect results. However, the mixed group took longer to response to a second series of questions than did the left and right movers. This post hoc finding may indicate inefficient hemispheric competition within the mixed group when subjects are asked to add another task to that of arithmetic problem-solving.
