Subject(s)
Cryosurgery , Light Coagulation , Retinal Artery/surgery , Humans , Retinal Diseases/surgeryABSTRACT
A 52-year-old woman had clinical findings of fundus flavimaculatus and a subretinal neovascular membrane that had involuted into a fibrous nodule beneath the foveola. Chronic destructive changes accompanying any disease involving the retinal pigmented epithelium may secondarily cause a lesion in Bruch's membrane, predisposing to subsequent subretinal neovascularization is a rarely observed manifestation in dystrophic diseases, which are usually slowly progressive.
Subject(s)
Pigment Epithelium of Eye/pathology , Retinal Degeneration/diagnosis , Retinal Vessels/pathology , Female , Fluorescein Angiography , Fundus Oculi , Humans , Middle Aged , Neovascularization, Pathologic , Retinal Degeneration/pathologyABSTRACT
A 32-year-old obese woman with hypertension and a three-year history of pseudotumor cerebri developed bilateral juxtapapillary subretinal neovascular membranes. To our knowledge, this is the first reported case of bilateral subretinal neovascular membranes complicating the course of this disease. The subretinal neovascular membrane in the left eye spontaneously involuted, but because the membrane in the right eye threatened the foveola, the patient underwent argon-laser photocoagulation. The subretinal fluid and hemorrhage progressively resolved, the membrane was replaced by fibrous tissue, and visual acuity improved. The pathogenesis of the subretinal neovascular membranes was presumably secondary to pressure deformity of the border of Bruch's membrane at the optic disk, creating a discontinuity of normal anatomic apposition of the chorioretinal layers. This anatomic dehiscence, coupled with hypoxia created by axonal tissue swelling and resultant impaired vascular perfusion of the tissues, led to the development of subretinal neovascular membranes.
Subject(s)
Neovascularization, Pathologic , Optic Disk/blood supply , Pseudotumor Cerebri/complications , Retinal Vessels/growth & development , Adult , Female , Fluorescein Angiography , Follow-Up Studies , Humans , Hypertension/complications , Laser Therapy , Obesity/complications , Papilledema/complications , Papilledema/diagnosis , Papilledema/surgery , Retinal Vessels/surgery , Visual AcuityABSTRACT
A 13-year-old boy with fundus flavimaculatus had a macular disease consisting of many transparent cystoid spaces which were not hyperfluorescent on fluorescein angiography. The Stiles-Crawford effect was abnormal, suggesting that the cystoid changes in the maculas created a disorientation of the patient's foveal retinal photoreceptors.
Subject(s)
Macula Lutea/pathology , Pigment Epithelium of Eye/pathology , Retinal Diseases/pathology , Visual Acuity , Adolescent , Color Perception Tests , Fluorescein Angiography , Humans , Male , Retinal Diseases/diagnosis , Retinal Diseases/physiopathology , Vision Tests/instrumentation , Vision Tests/methodsABSTRACT
A 4-year-old girl had the ichthyosis hystrix variant of the epidermal nevus syndrome with ocular fundus manifestations of Coats' disease. Her hearing was impaired because of serous otitis media and her visual acuity decreased because of hard yellow exudate in the macula as a result of decompensation and plasma leakage from the peripheral retinal vascular anomalies. Treatment of the vascular malformations with cryotherapy resulted in a reabsorption of the retinal edema and hard yellow exudate.
