Subject(s)
Amyotrophic Lateral Sclerosis/genetics , Point Mutation/genetics , Superoxide Dismutase/genetics , Amino Acid Sequence , Animals , Cattle , Female , Fishes , Genes, Dominant/genetics , Humans , Male , Mice , Middle Aged , Molecular Sequence Data , Polymorphism, Genetic , Sequence Alignment , SwineABSTRACT
We report the follow-up of a neonate with Pes equinovarus et adductus due to diastrophic dysplasia. The feet have been treated operatively by lengthening of the calcaneal tendon after initial redressement and casting. The normalized position is maintained by means of an removable plastic cast and later an instep raiser. Instructions for the maintenance are given.
Subject(s)
Bone Diseases, Developmental/complications , Foot Deformities, Congenital/complications , Foot Deformities, Congenital/rehabilitation , Female , Foot Deformities, Congenital/diagnostic imaging , Humans , Infant , Infant, Newborn , Orthotic Devices , RadiographyABSTRACT
A microvascular lesion characterized by extensive platelet aggregation, thrombosis, vascular damage with hemorrhages was found in the muscle of a 2-month-old boy with a myopathic form of the arthrogryposis syndrome. The lesion morphologically resembled the vascular leakage seen in immunologically mediated tissue injury. A degradative effect of proteases released during platelet and neutrophil aggregation on the muscle and joints is suggested.
