ABSTRACT
Clinical observations of 146 surgical patients have confirmed high informative value of fibrogastroduodenoscopy which could reveal ulcerations in 69% of the patients examined and thus choose the adequate treatment. A thorough study of acid-forming function of the stomach as well as determination of activity of lysosomal enzymes of the gastric juice has shown that hyperacidic state of the mucosa and high activity of alcaline phosphatase of the gastric juice may be considered as risk factors of the formation of acute ulcers.
Subject(s)
Abdomen/surgery , Peptic Ulcer/etiology , Postoperative Complications/etiology , Stress, Physiological/complications , Acute Disease , Gastric Acid/metabolism , Gastric Mucosa/metabolism , Humans , Stress, Physiological/physiopathology , Time FactorsABSTRACT
The gastric secretion was systematically examined in 58 patients during the first days after operations on organs of the abdominal cavity, 23 of them having it considerably increased. In three of these patients the operation was followed by gastric bleeding from acute ulcers. Higher gastric secretion was most frequently observed in patients with mechanical jaundice, purulent peritonitis and intestinal obstruction. Changes in the gastric secretion depend on the composition and volume of infusion therapy.