[Mechanisms of the development of cardiogenic vagosympathetic reflexes]. / O mekhanizmakh razvitiia kardiogennykh vagosimpaticheskikh refleksov.

Mechanisms of development of cardiogenic vagosympathetic depressor reflexes during adrenergic heart stimulation and local immune and ischemic damages of the left ventricle were studied in anesthetized dogs and cats by recording afferent and efferent impulsation from cardiac nerves as well as cardiodynamic indices. Impulse activity in cardiac nerves showed reciprocal changes: an increase in frequency of afferent impulsation in vagal nerves and inhibition of efferent impulsation in sympathetic nerves. The data obtained suggest that stimulation of heart mechanoreceptors due to the increase of myocardial contractility and asynergy of the left ventricle, is a triggering mechanism for reflex inhibition of sympathetic impulsation and depressor reflex.

[Functional state of the left ventricle of the heart in cardiocytotoxic shock]. / Funktsional'noe sostoianie levogo zheludochka serdtsa pri kardiotsitotoksicheskom shoke

Changes in the cardiodynamics and the contractile myocardium function under experimental shock caused by intracoronary injection of the anticardial cytotoxic serum were studied on 20 anesthetized dogs. Along with the symptoms of disturbance of the left ventricle function (a decrease of the systolic index, stroke work index of the left ventricle, rate of the intraventricular pressure rise, indices of myocardial contractility, ejection fraction) a decrease of the end-diastolic volume and pressure in the left ventricle was observed. These data show that disturbances in the cardiodynamics were cause not only by the cytotoxic heart damage, but also by derangement of the blood flow to the left heart.