1.
Histopathology
; 52(3): 389-92, 2008 Feb.
Article
in English
| MEDLINE
| ID: mdl-18081818
Subject(s)
Antigens, Neoplasm/analysis , Biomarkers, Tumor/analysis , Biotin/analysis , Cell Nucleus/pathology , Neoplasms/pathology , Neprilysin/analysis , Adenocarcinoma, Papillary/chemistry , Adenocarcinoma, Papillary/pathology , Cell Nucleus/chemistry , Female , Humans , Lung Neoplasms/chemistry , Lung Neoplasms/pathology , Metaplasia/pathology , Neoplasms/chemistry , Pancreatic Neoplasms/chemistry , Pancreatic Neoplasms/pathology , Pulmonary Blastoma/chemistry , Pulmonary Blastoma/pathology , Thyroid Neoplasms/chemistry , Thyroid Neoplasms/pathology
2.
J Clin Pathol
; 60(1): 98-100, 2007 Jan.
Article
in English
| MEDLINE
| ID: mdl-17213356
ABSTRACT
We report a case of a 9-cm mixed epithelial and stromal tumour of the kidney in an obese 70-year-old woman with diabetes. The ovarian-type stroma had a spindle cell component that was positive for progesterone receptors and had the hitherto unreported presence of abundant foci of luteinised stromal cells with characteristic immunohistochemical positivity to alpha-inhibin, calretinin, aromatase and gonadotropin-releasing hormone (GnRH) receptors. We conclude that the stromal component is identical to ovarian cortical stroma. We believe that ovarian-type stroma occurs in extragenital tumours as a result of an epithelial-stromal interaction in an environment of hormonal hyperstimulation.
Subject(s)
Kidney Neoplasms/pathology , Mixed Tumor, Malignant/pathology , Neoplasms, Glandular and Epithelial/pathology , Aged , Diabetes Mellitus, Type 2/complications , Female , Humans , Kidney Neoplasms/etiology , Mixed Tumor, Malignant/etiology , Neoplasms, Glandular and Epithelial/etiology , Obesity/complications , Stromal Cells/pathology
3.
Histopathology
; 49(3): 315-6, 2006 Sep.
Article
in English
| MEDLINE
| ID: mdl-16918982