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1.
Hillside J Clin Psychiatry ; 9(1): 47-54, 1987.
Article in English | MEDLINE | ID: mdl-3653842

ABSTRACT

Admission and mean 14-year follow-up Global Assessment Scale functioning were studied in 237 inpatients meeting DSM-III criteria for borderline (BPD) and schizotypal (SPD) personality disorders and compared to major affective disorder, schizophrenia and other diagnoses. BPD patients also meeting criteria for SPD functioned more poorly than other BPD or SPD patients at admission but improved their functioning at follow-up. Two BPD and SPD criteria which were associated with good follow-up functioning in BPD with SPD patients were found to predict poor admission functioning but good follow-up functioning in 18 of 237 former inpatients regardless of diagnosis.


Subject(s)
Borderline Personality Disorder/diagnosis , Hospitalization , Personality Disorders/diagnosis , Schizotypal Personality Disorder/diagnosis , Adult , Borderline Personality Disorder/psychology , Depressive Disorder/diagnosis , Depressive Disorder/psychology , Diagnosis, Differential , Female , Follow-Up Studies , Humans , Male , Manuals as Topic , Psychiatric Status Rating Scales , Retrospective Studies , Schizophrenia/diagnosis , Schizotypal Personality Disorder/psychology
6.
Biol Psychiatry ; 17(1): 33-40, 1982 Jan.
Article in English | MEDLINE | ID: mdl-7059637

ABSTRACT

The authors used a naturalistic design to replicate studies which validated the familial subtyping of primary depression. Ninety-three inpatients with unipolar depression had received the DST within 1 week of admission and were free of confounding medical problems. A blind rater assigned diagnoses based on chart material recorded before DST results were known. The results supported the earlier conclusions of Schlesser et al. With 8 AM sampling, 53% of familial pure depressive disease patients and 14% of depression spectrum disease patients were nonsuppressors. Differences, though smaller, remained significant with multiple sampling. Only 1 of 24 patients with secondary depression had an abnormal DST. Patterns of nonsuppression among patients with psychotic features resembled those of the larger group.


Subject(s)
Depressive Disorder/genetics , Dexamethasone , Hydrocortisone/blood , Adult , Alcoholism/genetics , Antisocial Personality Disorder/genetics , Bipolar Disorder/genetics , Depressive Disorder/blood , Depressive Disorder/diagnosis , Diagnosis, Differential , Female , Humans , Male
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