[Correction of bronchial hyperreactivity with Corinfar in patients with chronic renal insufficiency]. / Korrektsiia povyshennoi reaktivnosti bronkhov s pomoshchiu korinfara u bol'nykh s khronicheskoi pochechnoi nedostatochnost'iu.

As shown in the provocative tests in eighteen 24-42 year old chronics with renal insufficiency, corinfar pretreatment (20 mg sublingually) can protect against acetylcholine-induced bronchial hyperreactivity. This ability of the drug can be useful to reduce hyperreactivity of the bronchi of patients with chronic renal insufficiency.

[The role of pharmacological tests in detecting disorders in the bronchial patency and bronchial reactivity of patients with chronic glomerulonephritis]. / Rol' farmakologicheskikh testov v vyiavlenii narushenii bronkhial'noi prokhodimosti i reaktivnosti bronkhov u bol'nykh khronicheskim glomerulonefritom.

Data are reported of a study of the effect of atrovent, salbutamol and acetylcholine on bronchial patency and reactivity of the bronchi in 89 patients with glomerulonephritis (age: 17-49 years) with normal renal function and at the stage of chronic renal failure. The tests proved highly informative. Latent bronchospasm was found in 12.1% of patients with chronic glomerulonephritis. In 76.3% of patients at the stage of chronic renal failure hyperreactivity of the bronchi was found. The revealed changes require early diagnosis and treatment.

[The use of korinfar in a disorder of the patency of the bronchi and their elevated reactivity in patients with chronic kidney failure]. / Primenenie korinfara pri narushenii prokhodimosti bronkhov i povyshennoi ikh reaktivnosti u bol'nykh s khronicheskoi pochechnoi nedostatochnosti.

The author studied the effect of corinfar on bronchial patency and reactivity of the bronchi in 38 patients with chronic glomerulonephritis at the stage of chronic renal insufficiency. Age of the patients: from 26 to 48 years. Peroral administration of corinfar (dose: 10 mg) resulted in a clear improvement, mainly at the level of central bronchi, prevented the development of bronchial obstruction in the provocation test with acetylcholin, i e. possesses a protective effect. These properties of corinfar allow to recommend it for the treatment of renal insufficiency in patients showing bronchial disorders or/and bronchial hyperreactivity.