1.
Vaccine
; 39(42): 6210-6212, 2021 10 08.
Article
in English
| MEDLINE
| ID: mdl-34531083
ABSTRACT
Route of vaccine administration plays a role in extent and quality of immunogenicity. 790 military personnel accidentally received the first of two doses of Pfizer/BioNTech mRNA anti Covid-19 vaccine using a needle intended for subcutaneous administration. A serological blood test (on day 21, prior to the second intramuscular dose) was performed, analyzing whether immunological response was elicited. 98.2% demonstrated seroconversion. IgG titers were negatively correlated with age and did not correlate with BMI. Our results could help reassure providers confronted with a similar mistake and may even imply a possibly new and effective administration route.
Subject(s)
COVID-19 Vaccines , COVID-19 , Humans , SARS-CoV-2 , Seroconversion , Young Adult
2.
N Engl J Med
; 363(26): 2571-3, 2010 Dec 23.
Article
in English
| MEDLINE
| ID: mdl-21175337