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Org Biomol Chem ; 8(6): 1287-9, 2010 Mar 21.
Article in English | MEDLINE | ID: mdl-20204196

ABSTRACT

A concise total synthesis of enantiopure circumdatins E, H and J has been developed using a reductive cyclization of chiral N-prolinoyl-2-nitrobenzamides to construct the core quinazolinone ring.


Subject(s)
Benzodiazepinones/chemistry , Benzodiazepinones/chemical synthesis , Quinazolinones/chemical synthesis , Quinazolinones/chemistry , Stereoisomerism , Substrate Specificity
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