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Nucleic Acids Res ; 48(D1): D606-D612, 2020 01 08.
Article in English | MEDLINE | ID: mdl-31667520

ABSTRACT

The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases (https://www.patricbrc.org). PATRIC supports bioinformatic analyses of all bacteria with a special emphasis on pathogens, offering a rich comparative analysis environment that provides users with access to over 250 000 uniformly annotated and publicly available genomes with curated metadata. PATRIC offers web-based visualization and comparative analysis tools, a private workspace in which users can analyze their own data in the context of the public collections, services that streamline complex bioinformatic workflows and command-line tools for bulk data analysis. Over the past several years, as genomic and other omics-related experiments have become more cost-effective and widespread, we have observed considerable growth in the usage of and demand for easy-to-use, publicly available bioinformatic tools and services. Here we report the recent updates to the PATRIC resource, including new web-based comparative analysis tools, eight new services and the release of a command-line interface to access, query and analyze data.


Subject(s)
Bacteria/genetics , Computational Biology/methods , Databases, Genetic , Algorithms , Animals , Caenorhabditis elegans/genetics , Chickens/genetics , Drosophila melanogaster/genetics , Host-Pathogen Interactions/genetics , Humans , Internet , Macaca mulatta/genetics , Metagenomics , Mice , National Institute of Allergy and Infectious Diseases (U.S.) , Phenotype , Phylogeny , Rats , Swine/genetics , United States , Zebrafish/genetics
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