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1.
Ter Arkh ; 91(4): 28-36, 2019 May 16.
Article in English | MEDLINE | ID: mdl-31094473

ABSTRACT

AIM: to assess the diagnostic meaning of cardiac magnetic resonance imaging (CMR) in various clinical forms of myocarditis. MATERIALS AND METHODS: 11 (8 men, mean age 32.8±11.1 years) patients (pts), hospitalized with suspected acute coronary syndrome, while an acute myocardial infarction was excluded during the examination (group I); 48 pts (31 men, 43.1±12.7 years), with clinical and instrumental signs of dilated cardiomyopathy (DCM) - group II; and 20 patients (12 men, 39.5±14 years), with episodes of ventricular tachycardia (group III) underwent cardiac magnetic resonance imaging (CMRI). In 38 patients endomyocardial biopsy (EMB) was performed. RESULTS: According to EMB, signs of active myocarditis were revealed in 10 (34.5%) group II pts and in 3 (37.5%) group III pts; signs of resolved myocarditis - in 8 (27.6%) patients in group II and in 3 (37.5%); minimal morphological changes - in 11 (37.9%) patients of group II and in 2 (25%) patients of group III. In 9 (81.9%) patients of group I MRI data allowed to establish the diagnosis of acute myocarditis. Signs of active inflammation from MRI data were detected in myocardium 5 (10.4%) in group II pts and 7 (35%) in group III pts. In 22 (45.8%) pts in group II and 10 (50%), CMR data corresponded to the picture of resolved myocarditis. In 21 (43.8%) cases of group II and 3 (15%) of group III, MRI revealed minimal structural changes. In pts with clinical and instrumental signs of DCM and/or ventricular tachycardia MRI allows to identify signs of "active myocarditis" with a sensitivity of 37.5% with a specificity of 83.4%. At the same time, in cases of resolved myocarditis and minimal morphological changes MRI has high sensitivity (70 and 71.5%) and specificity (71.5 and 75%, respectively). CONCLUSION: CMR has high diagnostic significance in patients with infarct-like course of myocarditis. In patients with clinical syndrome of dilated cardiomyopathy or arrhythmias, the sensitivity of MRI in detecting active myocarditis is low (37.5%) with high specificity (83.4%). In cases of minimal structural changes in the myocardium and resolved inflammation, CMR is a good alternative to EMB.


Subject(s)
Cardiomyopathy, Dilated/diagnostic imaging , Magnetic Resonance Imaging/methods , Myocarditis/diagnostic imaging , Adult , Biopsy , Humans , Magnetic Resonance Spectroscopy , Male , Myocardium , Young Adult
2.
Ter Arkh ; 90(12): 101-106, 2018 Dec 30.
Article in English | MEDLINE | ID: mdl-30701841

ABSTRACT

Heart sarcoidosis diagnosis presents great difficulties due to the absence of specific clinical manifestations. Most often, the diagnosis is established during autopsy. Magnetic resonance imaging (MRI) of the heart with contrast enhancement is one of the most informative methods of intravital diagnosis of cardiac sarcoidosis. In this article, two clinical cases, shows the role of MRI of the heart with contrast enhancement in the diagnosis of cardiac sarcoidosis.


Subject(s)
Cardiomyopathies , Magnetic Resonance Imaging , Sarcoidosis , Cardiomyopathies/diagnostic imaging , Heart/diagnostic imaging , Humans , Sarcoidosis/diagnostic imaging
3.
Ter Arkh ; 88(8): 105-110, 2016.
Article in Russian | MEDLINE | ID: mdl-27636935

ABSTRACT

The paper describes a clinical case of a female patient with severe obstructive sleep apnea syndrome in the presence of congenital hemangioma of the face, soft palate, and tongue concurrent with paroxysmal atrial fibrillation and atrial flutter, paroxysmal supraventricular tachycardia, and sinoatrial block (maximally up to 3.9 sec). Continuous positive airway pressure therapy could reduce the number of paroxysms of atrial fibrillation and atrial flutter, supraventricular tachycardia and eliminate sinoatrial block.


Subject(s)
Arrhythmias, Cardiac , Continuous Positive Airway Pressure/methods , Head and Neck Neoplasms , Hemangioma , Mouth Neoplasms , Skin Neoplasms , Sleep Apnea, Obstructive , Arrhythmias, Cardiac/complications , Arrhythmias, Cardiac/diagnosis , Arrhythmias, Cardiac/prevention & control , Electrocardiography, Ambulatory/methods , Female , Head and Neck Neoplasms/complications , Head and Neck Neoplasms/pathology , Hemangioma/complications , Hemangioma/pathology , Humans , Magnetic Resonance Imaging/methods , Middle Aged , Mouth Neoplasms/complications , Mouth Neoplasms/pathology , Patient Care Management , Skin Neoplasms/complications , Skin Neoplasms/pathology , Sleep Apnea, Obstructive/complications , Sleep Apnea, Obstructive/diagnosis , Sleep Apnea, Obstructive/physiopathology , Sleep Apnea, Obstructive/therapy , Treatment Outcome
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