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Vopr Onkol ; 36(2): 171-6, 1990.
Article in Russian | MEDLINE | ID: mdl-2316199

ABSTRACT

The paper is concerned with the diagnostic value of a complex of laboratory micromethods for detection of tumors which were used in 421 subjects who had been endoscopically examined for gastrointestinal discomfort. The methods assured correct diagnosis in 61.1% and gave false-positive results in 35.6%. Ninety-seven percent of the latter group showed preneoplastic lesions of the stomach which must be followed up. Half of the patients with preneoplastic lesions of the stomach revealed changes in the physico-chemical properties of blood similar to those observed in gastric cancer patients. False-negative results were obtained in 3.8% of the whole group (far-advanced cancer). The sensitivity of the suggested complex of micromethods for gastric cancer detection was 86%, reliability--61 and specificity--52%.


Subject(s)
Biomarkers, Tumor/blood , Digestive System/physiopathology , Gastrointestinal Neoplasms/diagnosis , Clinical Laboratory Techniques/methods , Fibrinogen/analysis , Fluorescence , Gastrointestinal Neoplasms/blood , Humans , Mucoproteins/blood
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