Venous thromboembolism prophylaxis guideline compliance: a pilot study of augmented medication charts.

INTRODUCTION: Venous thromboembolism (VTE) is a common complication of hospital admission. The incidence of hospital-acquired deep vein thrombosis is approximately 10-40% amongst medical and general surgical patients without prophylaxis. Pulmonary embolism accounts for 5-10% of deaths in hospitalised patients, making hospital-acquired VTE the most common preventable cause of in-hospital death. Studies suggest that prophylactic measures are widely under- and inappropriately used. AIMS: We hypothesised that the introduction of a medication chart with a dedicated VTE prophylaxis section would improve compliance with local guidelines. METHODS: Trial medication charts were piloted over a 4-week period in one surgical and two medical wards. Data on compliance with hospital guidelines were collected before and after introduction using a detailed chart review. The difference in prescribing compliance was assessed with the Chi-squared test. RESULTS: 70 patients were assessed before and 38 after the introduction of the new charts. Initially, only 58.6% (n = 41) of patients' prescriptions were in compliance with local guidelines. In 28.6% (n = 20) of patients, VTE prophylaxis was needed and not prescribed. 7.1% (n = 5) of patients were prescribed an inappropriately low dose of low molecular weight heparin (LMWH) prophylaxis. 2.9% (n = 2) of patients were prescribed inappropriately high dose of LMWH prophylaxis. After introduction of the new medication chart, compliance with guidelines rose to 71% (n = 27, p = 0.09). CONCLUSION: Compliance with VTE guidelines is inadequate. Medication charts with specific sections on VTE assessment and prophylaxis may increase compliance with guidelines.

Basic surgical training in Ireland: the impact of operative experience, training program allocation and mentorship on trainee satisfaction.

BACKGROUND: Application to the Irish basic surgical training (BST) program in Ireland has decreased progressively over the past 5 years. We hypothesised that this decline was secondary to dissatisfaction with training correlated with reduced operative experience and lack of mentorship among BSTs. METHODS: An anonymous 15 question electronic survey was circulated to all BSTs appraising their impression of the operative experience available to them, their mentorship and their opinions of critical aspects of training. RESULTS: Fifty trainees responded to the survey. At the commencement of training 98 % (n = 43) intended to stay in surgery, decreasing to 79 % (n = 34) during the BST. Trainees who felt they had a mentor were three times more likely to be content in surgical training (OR 3.11; 95 % CI 0.94-10.25, P = 0.06). Trainees satisfied with their allocated rotation were more likely to be content in surgical training (OR 4.5; 95 % CI 1.03-19.6, P = 0.045). Individual trainee comments revealed dissatisfaction with operative exposure. CONCLUSION: Mentorship and satisfaction with allocated training rotation had a positive impact on trainee satisfaction and correlated with contentedness in surgical training. Operative experience is the main element that trainees report as lacking. This highlights the need for reform of the training system to improve current levels of mentorship and increase operative exposure to enhance its attractiveness to the best quality medical graduates.

Surgical audit using the POSSUM scoring tool in vascular surgery patients.

INTRODUCTION: Currently, crude morbidity and mortality rates are used to assess vascular surgical outcome. However, as a high-risk specialty, this may not be representative of quality of care. AIM: We evaluated the POSSUM score as a measure of performance in our vascular unit, and also its usefulness on an individual patient basis for predicting outcome. PATIENTS AND METHODS: A total of 106 patients were prospectively scored using the vascular-POSSUM score, and mean predicted and observed morbidity and mortality were compared with one-sample t tests. RESULTS: Receiver operator characteristic curves were used to determine if POSSUM scores were associated with the end-points of morbidity and mortality. Predicted and observed morbidity (41 and 35.8%, respectively) were not significantly different (P = 0.066). POSSUM did, however, over-predict mortality at 9.7% compared to the observed mortality of 5.7% (P = 0.021). While the discrimination for predicting morbidity was poor, POSSUM scores were significantly associated with mortality endpoints (area under ROC curve = 0.97250). POSSUM morbidity scores closely correlate with observed outcomes. CONCLUSION: Although POSSUM did over-predict mortality, high mortality scores may be useful for identifying patients at particularly high risk post-operatively. The POSSUM score is a useful adjunct to interpretation of morbidity and mortality statistics, and we would recommend its wider implementation for surgical audit.

Warfarin skin necrosis associated with protein S deficiency and a mutation in the methylenetetrahydrofolate reductase gene.

The use of warfarin is rarely complicated by skin necrosis. We describe a 50-year-old woman who presented with a left leg deep venous thrombosis and subsequent pulmonary embolism. She was initially anticoagulated with low-molecular weight heparin and subsequently warfarin. Within 4 days abdominal skin necrosis developed. Investigations revealed the presence of protein S deficiency and in addition, a mutation in the methylenetetrahydrofolate reductase gene (MTHFR). We present, to our best knowledge, the first case of warfarin skin necrosis associated with a methylenetetrahydrofolate reductase mutation.