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2.
J Clin Neurosci ; 21(11): 1990-3, 2014 Nov.
Article in English | MEDLINE | ID: mdl-24913930

ABSTRACT

We report a 44-year-old with progressive quadriparesis due to a dumbbell malignant peripheral nerve sheath tumour (MPNST) of the second cervical nerve, 17 years after whole brain radiotherapy for a pineal germinoma. To our knowledge this is the first case of radiation induced high cervical MPNST arising from a benign neurofibroma.


Subject(s)
Cervical Plexus/radiation effects , Cranial Irradiation/adverse effects , Nerve Sheath Neoplasms/diagnosis , Nerve Sheath Neoplasms/etiology , Neurofibroma/complications , Quadriplegia/etiology , Spinal Cord Neoplasms/complications , Adult , Germinoma/radiotherapy , Humans , Magnetic Resonance Imaging/methods , Male , Nerve Sheath Neoplasms/complications , Nerve Sheath Neoplasms/pathology , Nerve Sheath Neoplasms/surgery , Neurofibroma/etiology , Pinealoma/radiotherapy , Spinal Cord Neoplasms/etiology
3.
J Clin Neurosci ; 16(9): 1230-2, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19505828

ABSTRACT

We report a 30-year-old male who had undergone a renal transplant and suffered with secondary hyperparathyroidism. He presented with back pain and minimal neurological deterioration, caused by a thoracic brown tumour. The imaging findings, surgical treatment of the spinal lesion and outcome are discussed. We also discuss primary medical therapy and suggest a rational approach to further imaging of patients in whom brown tumour is suspected.


Subject(s)
Kidney Transplantation , Spinal Neoplasms/complications , Adult , Gait/physiology , Humans , Hyperparathyroidism, Secondary/complications , Kidney Failure, Chronic/complications , Kidney Failure, Chronic/surgery , Magnetic Resonance Imaging , Male , Spinal Cord Compression/etiology , Spinal Cord Compression/surgery , Spinal Neoplasms/pathology , Spinal Neoplasms/surgery
4.
J Clin Neurosci ; 16(8): 1095-6, 2009 Aug.
Article in English | MEDLINE | ID: mdl-19428258

ABSTRACT

In 1998, one of us (MJM) published an article discussing several patients with Osler-Weber-Rendu Syndrome or hereditary haemorrhagic telangiectasia with secondary cerebral complications. These were intracerebral haemorrhage, ischaemic infarct and intracerebral abscess. We outlined the background of the syndrome as well as its genotype and predicted an increasingly important role for genetic testing. Our aim in this paper is to examine the progress of one of the patients as well as recommending follow-up guidelines for patients with pulmonary arteriovenous fistulae that have been treated.


Subject(s)
Arteriovenous Fistula/therapy , Brain Abscess/therapy , Gram-Positive Bacterial Infections/therapy , Lung Diseases/therapy , Peptostreptococcus , Telangiectasia, Hereditary Hemorrhagic/therapy , Arteriovenous Fistula/pathology , Brain/pathology , Brain Abscess/pathology , Follow-Up Studies , Gram-Positive Bacterial Infections/pathology , Humans , Lung Diseases/pathology , Magnetic Resonance Imaging , Male , Middle Aged , Telangiectasia, Hereditary Hemorrhagic/pathology
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