ABSTRACT
UNLABELLED: The purpose of this study is to evaluate symptomatology, endoscopic and histopathologic changes of Helicobacter pylori infection and gastritis lesions without Helicobacter pylori infection on children diagnosed with celiac disease. MATERIAL AND METHOD: 15 children under gluten-free diet were selected and, because of the recurrence of the dyspeptic syndrome, an upper digestive endoscopy associated with histopathologic exam was performed. Considering the histopathologic result we made two groups: first group (8 children with celiac disease and Helicobacter pylori infection) and second group (7 children with celiac disease without Helicobacter pylori infection, but associated with gastritis lesions). RESULTS: The main symptom was diffuse abdominal pain in both groups. The endoscopic antrum aspects were congestive with striped aspect (first group--12.5%, second group--42.9%) and congestive with nodulation (first group--25%, second group--14.3%). The histopathologic diagnosis were: moderate active chronic pangastritis (first group--25%, second group--14.3%) moderate active chronic gastritis (first group--25%,second group--14.3%), lymphocytic gastritis (first group--12.5%, second group--14.3%). CONCLUSION: The histopathologic exam remains the gold standard for celiac disease, gastritis lesions and Helicobacter pylori infection.
Subject(s)
Celiac Disease/complications , Celiac Disease/pathology , Helicobacter Infections/pathology , Helicobacter pylori , Abdominal Pain/microbiology , Adolescent , Celiac Disease/diagnosis , Celiac Disease/microbiology , Child , Child, Preschool , Diet, Gluten-Free , Endoscopy, Gastrointestinal , Female , Gastritis/microbiology , Gastritis/pathology , Helicobacter Infections/complications , Helicobacter Infections/diagnosis , Helicobacter pylori/isolation & purification , Humans , Male , Retrospective Studies , Risk Factors , Severity of Illness IndexABSTRACT
UNLABELLED: The authors present the results of retroprospective epidemiological, clinical and laboratory diagnosis on toxocariasis cases hospitalized in the Paediatric Diseases Clinic of Iasi, between January 2005- June 2008. MATERIAL AND METHOD: The study included a number of 228 children. RESULTS: Cutaneous manifestations were present in 65 children: 30 boys (46.15%) and 34 girls (52.30%), with a slight advance of the urban environment (53.84%). The age distribution highlighted a predominance of 1-6 age (66.15%). Cutaneous manifestations were pruritus, urticaria, atopic dermatitis, prurigo. The distribution of toxocariasis in children patients in Moldavia, Romania, highlighted a predominance in Iasi. The laboratory diagnosis of the children with cutaneous manifestations: hypereosinophilia was present on 87.69% of the children associated with hyperleucocytosis. All the patients were serologicaly confirmed with toxocariasis. The children responded well to treatment with albendazole.
Subject(s)
Inpatients/statistics & numerical data , Skin Diseases, Parasitic/parasitology , Toxocara , Toxocariasis/complications , Adolescent , Albendazole/therapeutic use , Animals , Anthelmintics/therapeutic use , Child , Child, Preschool , Dermatitis, Atopic/parasitology , Eosinophilia/parasitology , Female , Hospitals, Pediatric , Hospitals, University , Humans , Infant , Infant, Newborn , Male , Retrospective Studies , Risk Factors , Romania/epidemiology , Skin Diseases, Parasitic/diagnosis , Skin Diseases, Parasitic/drug therapy , Skin Diseases, Parasitic/epidemiology , Skin Diseases, Parasitic/immunology , Toxocara/immunology , Toxocariasis/diagnosis , Toxocariasis/drug therapy , Toxocariasis/epidemiology , Toxocariasis/immunology , Treatment Outcome , Urticaria/parasitologyABSTRACT
UNLABELLED: The authors present the results of retroprospective clinical and laboratory diagnosis on toxocariasis cases hospitalized in the Paediatric Diseases Clinic of Iasi, between January 2005-June 2008. MATERIAL AND METHOD: The study included a number of 228 children. RESULTS: The most frequent clinical manifestation was pulmonary symptoms 80.70%: dyspneea, wheesing, asthma, cough, interstitial pneumonitis. The most frequent digestive symptoms were abdominal pain 41.22%, hepatosplenomegaly 29.38%; cutaneous manifestations were pruritus and urticaria. The laboratory diagnosis: hypereosinophilia was present at 94.73% childrens associated with hyperleucocytosis and hyper-gammaglobulinemia. All the patients were serologic confirmed with toxocariasis. The children responded well to treatment with albendazole.
Subject(s)
Albendazole/therapeutic use , Anthelmintics/therapeutic use , Toxocariasis/diagnosis , Toxocariasis/drug therapy , Abdominal Pain/parasitology , Animals , Asthma/parasitology , Child , Cough/parasitology , Dyspnea/parasitology , Eosinophilia/parasitology , Hepatomegaly/parasitology , Humans , Hypergammaglobulinemia/parasitology , Leukocytosis/parasitology , Lung Diseases, Interstitial/parasitology , Pruritus/parasitology , Respiratory Sounds/etiology , Retrospective Studies , Romania , Splenomegaly/parasitology , Toxocara/isolation & purification , Toxocariasis/complications , Treatment Outcome , Urticaria/parasitologyABSTRACT
Celiac disease, also known as gluten-sensitive enteropathy, is an autoimmune enteropathy caused by the ingestion of gluten-containing grains in susceptible subjects. The authors present a 3 years and 5 months old girl diagnosed with celiac disease at 1 year and 5 months old. Initially, the evolution after gluten-free diet was favorable. After 2 years the child presented abdominal pain and anorexia. The IgA antigliadin antibodies had normal values. The gastric biopsy found Helicobacter pylori gastritis. After treatment for Helicobacter pylori eradication the symptoms disappeared.
