ABSTRACT
Hypophyseal apoplexy is not always easy to confirm morphologically or analytically. We present a patient with Cushing's syndrome due to hypophyseal apoplexy and optochiasmic pachyarachnoiditis which produced serious visual alterations. The adenoma necrotized behind an area of hypophyseal apoplexy which cured the patient's Cushing's disease. The second case was admitted with hypophyseal apoplexy, presenting hypophyseal tumoration with signs of hemorrhage and subsequent panhypopituitarism.
Subject(s)
Adenoma/pathology , Pituitary Apoplexy/pathology , Pituitary Neoplasms/pathology , Adenoma/complications , Adult , Arachnoiditis/complications , Arachnoiditis/pathology , Cushing Syndrome/etiology , Cushing Syndrome/pathology , Female , Humans , Hypopituitarism/etiology , Hypopituitarism/pathology , Male , Middle Aged , Optic Chiasm , Pituitary Apoplexy/complications , Pituitary Apoplexy/etiology , Pituitary Neoplasms/complicationsABSTRACT
Suprarenal carcinoma is an unusual entity, rarely surpassing 4,000 gr. In general, tumors of such big size are not functional. We present a case of a 31-years-old woman with a suprarenal carcinoma weighting 5,200 gr, in which hormonal production was clinically and biochemically demonstrated.
Subject(s)
Adrenal Gland Neoplasms/diagnosis , Adrenal Gland Neoplasms/metabolism , Adrenal Gland Neoplasms/pathology , Adult , Female , Humans , KidneyABSTRACT
Over a period spanning six months, 69 patients with lithiasis were selected for evaluation of mineral metabolism. Hypercalciuria, particularly renal, was the metabolic disorder that was commonly detected. A high incidence of altered uric acid metabolism was also observed. The importance of correct diagnosis and treatment of hyperparathyroidism is underscored because of the extraordinary benefit afforded to these patients. Correct patient selection has resulted in a lower incidence of those with normal metabolic parameters and has thus maximized the usefulness of these studies.
Subject(s)
Kidney Calculi/metabolism , Acidosis, Renal Tubular/complications , Adolescent , Adult , Aged , Calcium/urine , Child , Cystinuria/complications , Female , Humans , Hyperparathyroidism/complications , Hyperparathyroidism/diagnosis , Hyperparathyroidism/therapy , Kidney Calculi/etiology , Male , Middle Aged , Oxalates/urine , Oxalic Acid , Recurrence , Uric Acid/metabolismABSTRACT
We report 5 clinical cases of primary hypothyroidism or premixedema with associated pituitary lesion. Before treatment was started with L-thyroixine (L-T4) pituitary hormones were examined and an X-ray of the silla turca as well as a CT scan of the hypophysis (CTH) was done. Once supplementation treatment was started hormone levels normalized. In three out of the 5 cases, CT scan done after establishing therapy, showed empty silla turca. Therefore, me stress the importance of closely examining the pituitary gland in patients with untreated primary hypothyroidism.
