ABSTRACT
Mast cells (MCs) can release a variety of biologically active mediators under different circumstances, such as fever or vaccination. Our aim was to evaluate the incidence and severity of MC activation symptoms induced by SARS-CoV-2 virus (COVID-19) infection and vaccination in a cohort of 92 pediatric patients with cutaneous mastocytosis. Our findings support previous evidence on the safety of COVID-19 infection and vaccination in patients with MC disorders.
Subject(s)
COVID-19 Vaccines , COVID-19 , Mastocytosis, Cutaneous , SARS-CoV-2 , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , COVID-19/prevention & control , COVID-19 Vaccines/adverse effects , Cross-Sectional Studies , Retrospective Studies , VaccinationABSTRACT
The Carabidae (Insecta: Coleoptera) type species of Entomological Collection of the Entomology Institute housed in the Zoology Area of Miguel Lillo Foundation (FML), Tucumán, Argentina, were examined and listed. This collection is considered one of the most prestigious collections in Argentina and South America. The Carabidae family is represented by 545 species, with ten holotypes, one allotype, 12 cotypes, and 65 paratypes, which correspond to 35 species. Complete information and images for each species are given.
Subject(s)
Coleoptera , Animals , Argentina , Insecta , Entomology , ZoologySubject(s)
Biosimilar Pharmaceuticals , Hidradenitis Suppurativa , Mevalonate Kinase Deficiency , Psoriasis , Humans , Adalimumab/adverse effects , Ustekinumab/adverse effects , Hidradenitis Suppurativa/complications , Hidradenitis Suppurativa/drug therapy , Hidradenitis Suppurativa/chemically induced , Biosimilar Pharmaceuticals/adverse effects , Psoriasis/complications , Psoriasis/drug therapy , Psoriasis/chemically inducedABSTRACT
Idiopathic facial aseptic granuloma (IFAG) is characterized by the appearance of a painless reddish nodule in the facial region and is exclusive to children. It is usually located on the cheek. The resolution of these lesions is usually spontaneous in months and they heal without leaving a scar or with minimal scarring. Its etiology is unknown. The diagnosis is fundamentally clinical, although sometimes complementary tests such as ultrasound can be used. This pathology presents a chronic but benign clinical course with spontaneous resolution, so in these cases a wait-and-see approach is preferred (AU)
Idiopathic facial aseptic granuloma (IFAG) is characterized by the appearance of a painless reddish nodule in the facial region and is exclusive to children. It is usually located on the cheek. The resolution of these lesions is usually spontaneous in months and they heal without leaving a scar or with minimal scarring. Its etiology is unknown. The diagnosis is fundamentally clinical, although sometimes complementary tests such as ultrasound can be used. This pathology presents a chronic but benign clinical course with spontaneous resolution, so in these cases a wait-and-see attitude is preferred. (AU)
Subject(s)
Humans , Male , Child, Preschool , Granuloma/diagnostic imaging , Face , Remission, Spontaneous , UltrasonographyABSTRACT
Postpartum depression (PPD) affects 13% of mothers and can have a major impact on their lives and those of their children. However, most cases go undiagnosed, and the risk factors for this underdiagnosis are not yet fully known. We intended to analyze the influence of different sociodemographic and health factors associated with symptoms of postpartum depression. Data from the New York City Pregnancy Risk Assessment Monitoring System (PRAMS) for 2016-2017 were analyzed. 618 women met the inclusion criterion of recurring depressive symptoms. Most women who experienced PPD symptoms did not seek help. Seeking help was a much better predictor of the diagnosis of PPD when compared to questions regarding symptoms. The most important factors related to a decreased risk of not asking for help were having a previous mental health history and having doctor visits for a chronic illness. The racial group most at risk of not asking for help were Asian/Pacific Islander (API) women. Interventions aimed at reducing the stigma and increasing knowledge of PPD should be incorporated into the antenatal education of expectant mothers, particularly among women who may not have previously sought care for mental or chronic illnesses.
Subject(s)
Depression, Postpartum , Help-Seeking Behavior , Adult , Depression, Postpartum/epidemiology , Depression, Postpartum/prevention & control , Female , Humans , New York City/epidemiology , Pregnancy , Psychology , Risk Assessment , Young AdultABSTRACT
BACKGROUND AND PURPOSE: The exercise training included in pulmonary rehabilitation (PR) programmes improves exercise capacity and quality of life in patients with chronic obstructive pulmonary disease (COPD). Nevertheless, the duration of these effects is limited, and the implementation of PR is still insufficient. Moreover, the physical activity level of COPD patients is low, and it is not modified with the classic PR programmes. The purpose of this study was to assess the effects of a community-based PR programme designed to increase physical activity in COPD patients. METHODS: Stable COPD patients were assigned to either an experimental group (EG, n = 17) who followed a community-based 8-week programme consisting of exercise training through walking and a plan to increase activity, using a pedometer for feedback; or a control group (n = 16), who followed general recommendations to walk more every day. The following were evaluated postintervention, after 3 months, and after 12 months: exercise capacity (endurance shuttle test [EST]), physical activity (steps/day and modified Baecke questionnaire), quality of life (St. George's Respiratory Questionnaire [SGRQ]), dyspnoea (modified Medical Research Council scale), and exacerbations. RESULTS: Postintervention, the EG showed significant improvements in EST times (7.6 min [4.4, 10.7]), distance (549 m [282, 815]; p < 0.01, both), number of steps (3,361 [1,553, 5,118]), and Baecke scores (1.6 [0.2, 3.1], p < 0.01). SGRQ scores decreased (-5.4 [-8.6, -2.4], p < 0.01). These results remained evident after 3 and 12 months (p < 0.01). There were no differences between the groups nor in the exacerbations or dyspnoea. A significant association was found between increase in physical activity level, improvement in exercise capacity, and quality of life during the period monitored. CONCLUSIONS: A community-based programme of exercise training through walking and increased physical activity, using pedometers as feedback, produces short- and long-term improvements in exercise capacity, physical activity level, and quality of life in COPD patients.
