Subject(s)
Humans , Female , Middle Aged , Schizencephaly/diagnostic imaging , Magnetic Resonance Imaging , ElectroencephalographyABSTRACT
No disponible
Subject(s)
Humans , Male , Adolescent , Angiofibroma/surgery , Nasopharyngeal Neoplasms/surgery , Postoperative Complications/etiology , Rhabdomyolysis/etiology , Time FactorsABSTRACT
No disponible
No disponible
Subject(s)
Humans , Female , Aged , Anticonvulsants/adverse effects , Hyponatremia/chemically induced , Anticonvulsants/administration & dosage , Seizures/drug therapy , Hyponatremia/diagnosis , Inappropriate ADH Syndrome/chemically induced , Inappropriate ADH Syndrome/diagnosisABSTRACT
No disponible
No disponible
Subject(s)
Female , Humans , Fistula/complications , Fistula/diagnosis , Biliary Tract Diseases/complications , Biliary Tract Diseases/diagnosis , Piperacillin/therapeutic use , Pleural Effusion/complications , Pleural Effusion/drug therapy , Gallbladder/surgery , Bile Ducts/pathology , Hypertension/complications , Pancreatitis/complications , Postoperative Complications/surgery , Radiography, Thoracic/methodsABSTRACT
No disponible
Subject(s)
Male , Middle Aged , Humans , Hemobilia/complications , Hemobilia/diagnosis , Hemobilia/surgery , Hemorrhage/complications , Hemorrhage/etiology , Adenoma/etiology , Ureterostomy/methods , Endoscopy, Digestive System/methods , Tomography, Emission-Computed/methods , Urinary Bladder Neoplasms/complications , Gastrointestinal Hemorrhage/complications , Hematemesis/complications , Ventricular Fibrillation/complications , Cardiopulmonary Resuscitation/methods , Adenoma/complications , Hematemesis/diagnosis , Angiography/methods , Abdomen/pathology , Abdomen , Adenoma, Bile Duct/complicationsABSTRACT
We describe the case of a 67 year old male with chronic hepatitis C on treatment with pegylated interferon and ribavirin who, after two and a half months of combined treatment, presented with a picture of acute mesenteric vein thrombosis that required urgent surgery. It re-occurred several days later and was his cause of death. In the thrombophilia study carried out immediately after surgery a decrease in protein C and S was considered as a cause of hypercoagulability. Protein C and S deficiency, natural anticoagulants synthesised in the liver, in patients without hepatic disease is a known cause of mesenteric thrombosis. Its decrease has also been described in the context of chronic hepatic diseases, including C virus chronic hepatitis, although it is not known for sure if this hypercoagulability state is a primary or secondary manifestation. Chronic hepatitis C and treatment with interferon has often been associated with a procoagulant state, and on many occasions due to different factors and mechanisms.
Subject(s)
Antiviral Agents/adverse effects , Hepatitis C, Chronic/complications , Interferon-alpha/adverse effects , Mesenteric Vascular Occlusion/etiology , Polyethylene Glycols/adverse effects , Protein C Deficiency/etiology , Protein S Deficiency/etiology , Ribavirin/therapeutic use , Thrombophilia/etiology , Venous Thrombosis/etiology , Aged , Antiviral Agents/therapeutic use , Drug Therapy, Combination , Fatal Outcome , Gram-Negative Bacterial Infections/etiology , Hemoperitoneum/etiology , Hepatitis C, Chronic/blood , Hepatitis C, Chronic/drug therapy , Humans , Interferon-alpha/therapeutic use , Male , Mesenteric Vascular Occlusion/surgery , Mesenteric Veins , Pneumonia, Bacterial/etiology , Polyethylene Glycols/therapeutic use , Recurrence , Respiration, Artificial/adverse effects , Stenotrophomonas maltophilia , Thrombectomy , Venous Thrombosis/surgeryABSTRACT
Describimos el caso de un varón de 67 años de edad, con una hepatitis C crónica en tratamiento con interferón pegilado y ribavirina, que presentó, tras 2,5 meses de terapia combinada, un cuadro de trombosis mesentérica aguda que requirió cirugía urgente; tuvo una recidiva días después, que fue la causa de su fallecimiento. En el estudio de trombofilia durante el postoperatorio inmediato se constató un descenso de las proteínas C y S como causa de hipercoagulabilidad. La deficiencia de proteínas C y S, anticoagulantes naturales sintetizados en el hígado, en pacientes sin hepatopatía es una causa conocida de trombosis mesentérica. También se ha descrito su disminución en el contexto de hepatopatías crónicas, entre ellas la hepatitis crónica por el virus C, aunque no se conoce con certeza si este estado de hipercoagulabilidad es un fenómeno primario o secundario. La hepatitis C crónica y el tratamiento con interferón se han asociado con frecuencia a un estado procoagulante por distintos factores y mecanismos
We describe the case of a 67 year old male with chronic hepatitis C on treatment with pegylated interferon and ribavirin who, after two and a half months of combined treatment, presented with a picture of acute mesenteric vein thrombosis that required urgent surgery. It re-occurred several days later and was his cause of death. In the thrombophilia study carried out immediately after surgery a decrease in protein C and S was considered as a cause of hypercoagulability. Protein C and S deficiency, natural anticoagulants synthesised in the liver, in patients without hepatic disease is a known cause of mesenteric thrombosis. Its decrease has also been described in the context of chronic hepatic diseases, including C virus chronic hepatitis, although it is not known for sure if this hypercoagulability state is a primary or secondary manifestation. Chronic hepatitis C and treatment with interferon has often been associated with a procoagulant state, and on many occasions due to different factors and mechanisms
Subject(s)
Male , Aged , Humans , Hepatitis C, Chronic/complications , Thrombosis/complications , Protein S Deficiency/complications , Protein C Deficiency/complications , Hepatitis C, Chronic/drug therapy , Ribavirin/adverse effects , Interferons/adverse effects , Mesenteric Arteries/injuriesABSTRACT
BACKGROUND: Portal vein thrombosis in adults is usually related to cirrhosis. There are several possible therapies. including anticoagulation, transjugular intrahepatic portosystemic shunt, balloon dilatation, local and systemic fibrinolytics agents. Hypercoagulable states are also reported in association with this disease entity. Eosinophilia may activate platelets and promote thrombosis due to proteins contained in intracytoplasmic granules, such as eosinophil cationic protein and major basic protein. There is only one paper in the medical literature linking eosinophilia and portal vein thrombosis. CASE REPORT: We present here the case of a middle-age woman with idiopathic eosinophilia and acute portal vein thrombosis with massive venous thrombosis, involving the mesenteric, splenic, inferior cava, iliac and femoral veins, successfully treated with systemic streptokinase. CONCLUSIONS: Acute portal vein thrombosis with associated mesenteric and splenic vein thrombosis is a potentially lethal coagulation disorder that can be treated successfully with systemic streptokinase.
Subject(s)
Budd-Chiari Syndrome/diagnostic imaging , Budd-Chiari Syndrome/drug therapy , Portal Vein/pathology , Streptokinase/therapeutic use , Thrombolytic Therapy , Budd-Chiari Syndrome/etiology , Eosinophilia/complications , Female , Humans , Middle Aged , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
No disponible
No disponible
Subject(s)
Female , Middle Aged , Humans , Myocardial Infarction/etiology , Coronary Vessels/injuries , Rupture, Spontaneous/complications , Coronary Angiography , ElectrocardiographySubject(s)
Deamino Arginine Vasopressin/adverse effects , Diabetes Insipidus/chemically induced , Diabetes Insipidus/complications , Hemostatics/adverse effects , Histiocytosis, Langerhans-Cell/complications , Hyponatremia/chemically induced , Hyponatremia/complications , Water Intoxication/chemically induced , Administration, Intranasal , Adult , Deamino Arginine Vasopressin/administration & dosage , Female , Hemostatics/administration & dosage , Humans , Severity of Illness IndexABSTRACT
No disponible
Subject(s)
Adult , Aged , Male , Female , Humans , Water Intoxication , Pericardium , Diabetes Insipidus , Administration, Intranasal , Hemostatics , Histiocytosis, Langerhans-Cell , Hyponatremia , Severity of Illness Index , Histiocytoma, Benign Fibrous , Deamino Arginine Vasopressin , Heart NeoplasmsABSTRACT
No disponible
