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J Clin Microbiol ; 38(1): 264-7, 2000 Jan.
Article in English | MEDLINE | ID: mdl-10618098

ABSTRACT

The P (VP4) and G (VP7) genotypes of 167 group A rotavirus strains obtained during the period 1996 to 1998 from 149 children living in a suburban community in Guinea-Bissau, western Africa, were determined by the reverse transcription-PCR technique. A total of nine combinations including five different P types and five different G types were identified. The globally common genotype pairs P[8], G1; P[4], G2; P[8], G3 and P[8], G4 were underrepresented in this study area. We found a substantial year-to-year variation in the occurrence of the genotype combinations. In 1996 and 1997, P[6], G2 was the most frequent, whereas P[8], G1 was more common in 1998. The unusual type P[9], G3 and a few mixed infections were detected. Sixteen percent of the rotavirus-positive samples were nontypeable.


Subject(s)
Antigens, Viral , Capsid Proteins , Capsid/genetics , Rotavirus Infections/virology , Rotavirus/classification , Rotavirus/genetics , Child, Preschool , Feces/virology , Genotype , Guinea-Bissau , Humans , Infant , Infant, Newborn , Reverse Transcriptase Polymerase Chain Reaction
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