[The role of serum amyloid A in the early diagnosis of acute coronary syndrome]. / Rola bialka amyloidowego A we wczesnej diagnostyce ostrego zespolu wiencowego.

The aim of this study was to evaluate diagnostic usefulness of serum amyloid A (SAA) in diagnosis of acute myocardial infarction (AMI) in group of patients with stenocardia. The study was carried out in group of 62 patients admitted to Emergency Unit of 5-th Military Hospital in Krakow. The study group consisted of 24 (38.7%) patients with unstable angina pectoris and 38 (61.3%) with acute myocardial infarction. It was found that SAA concentration significantly increases in patients with AMI: 136.0 +/- 220.6 mg/L versus 7.38 +/- 8.8 mg/L in unstable angina pectoris (p < or = 0.009). Studies of mutual relations between SAA levels and cardiac markers have shown a remarkably positive correlation between SAA and troponin I (r = 0.39; p < or = 0.01) and negative correlation between SAA concentrations and platelet count decrease (r = -0.55; p < or = 0.01).

[Real profits of CKMBmass determination in early differentiation of acute coronary syndrome in patients admitted to the emergency unit]. / Praktyczne wykorzystanie oznaczania CKMBmass we wczesnym róznicowaniu postaci ostrego zespolu wiencowego u chorych zglaszajacych sie do Izby Przyjec Oddzialu Ratunkowego.

The aim of this study was to evaluate actual diagnostic profits of CKMBmass concentration in diagnosis of acute myocardial infarction (AMI) in the group of patients admitted to the Emergency Unit with stenocardia and comparison to CKMB activity test. The study carried out in a group of 53 patients admitted to the Emergency Unit of 5-th Military Hospital in Krakow. The study group consisted of 28 (52.8%) of patients with acute myocardial infarction and 25 (47.2%) with unstable angina pectoris. It was found that diagnostic sensitivity of both parameters (CKMBmass 70.8% and CKMB 67.8%) are equivalent for early diagnosis of acute coronary syndrome in the Emergency Unit.

[The role of serum troponin I and high sensitivity C-reactive protein concentrations in early diagnosis of acute coronary syndrome in patients admitted to Emergency Unit]. / Rola troponiny I oraz ultraczulego bialka C-reaktywnego we wczesnej ocenie ryzyka u chorych z ostrym zespolem wiencowym zglaszajacych sie do izby Przyjec Oddzialu Ratunkowego.

The aim of this study was to show clinical benefit of simultaneous determinations of troponin I (cTnI) and high sensitivity C-reactive protein (hsCRP) at early diagnosis in the group of patients with stenocardia admitted to the Emergency Unit of 5-th Military Hospital in Krakow. The study group consisted of 38 (51.3%) patients with acute myocardial infarction (AMI) and 36 (48.6%) with unstable angina pectoris. ROC function analysis for cTnI (cutoff value 0.69 ng/mL) and hsCRP (3.33 mg/L) indicated significant amelioration of diagnostic sensitivity into 84.9% at early diagnostics of AMI in group of patients with acute coronary syndrome (ACS). Moreover, studies of mutual relationship between elevated levels of hsCRP and cTnI concentrations have shown a remarkably positive correlation (r = 0.90; p < or = 0.01) in the group of patients with AMI.