Reversal of negative lepromin reactions following use of tuberculosis vaccine irradiated

Fifty healthy, lepromin-negative individuals living with leprous persons were vaccinated with Tuberculosis Vaccine, Irradiated. In 47 of them the lepromin reaction became positive after one or two courses of the vaccine. We believe that Tuberculosis Vaccine, Irradiated, may prove to be of value because it changes Mitsuda-negative individuals to positive reactors.