Subject(s)
Pregnancy Complications, Infectious , Weil Disease/diagnosis , Adult , Female , Fetal Death , Humans , PregnancySubject(s)
Osteomyelitis/complications , Pulmonary Embolism/complications , Staphylococcal Infections/complications , Venous Thrombosis/etiology , Acute Disease , Child, Preschool , Emergency Service, Hospital , Fever/complications , Fibula/diagnostic imaging , Fibula/pathology , Fibula/surgery , Humans , Iliac Vein/diagnostic imaging , Iliac Vein/pathology , Lung/diagnostic imaging , Lung/pathology , Magnetic Resonance Imaging , Male , Radiography , Staphylococcus aureus/isolation & purification , UltrasonographyABSTRACT
Lymphocytic cutaneous vasculitis associated with a haematological malignancy has rarely been reported. Here, we describe a 61 year-old woman with chronic lymphocytic leukemia (CLL) who presented with cutaneous lesions on both hands. These lesions improved after all combination chemotherapy courses and recurred before each course. Repetitive skin biopsies revealed lymphocytic vasculitis. After 7 courses of chemotherapy, she had a complete remission. Skin lesions disappeared and did not recur. The cyclic pattern of lymphocytic vasculitis and its relation with CLL disease activity are interesting clinical features in this case.
Subject(s)
Leukemia, Lymphocytic, Chronic, B-Cell/complications , Vasculitis/etiology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Female , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy , Middle Aged , Paraneoplastic Syndromes/etiology , Remission Induction , Skin Diseases, Vascular/etiology , T-Lymphocytes/pathologyABSTRACT
Nasal-type T/natural killer (NK)-cell lymphoma, a distinct clinicopathological entity is highly associated with Epstein-Barr virus which shows an aggressive course. We present a CD56+ nasal-type T/(NK)-cell lymphoma case with systemic manifestations of rhabdomyolysis and polyserositis who died of multiorgan failure shortly after his admission to hospital in spite of adequate chemotherapy and supportive care.
