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Acta Reumatol Port ; 40(2): 190-2, 2015.
Article in English | MEDLINE | ID: mdl-26219972

ABSTRACT

Propylthiouracil (PTU) is known to induce antineutrophil cytoplasmatic antibody (ANCA) seropositivity; however, small vessel vasculitis (SVV) with pulmonary and renal involvement is rare. We present the case of an 81-year-old woman on PTU treatment due to toxic nodular goitre who developed alveolar hemorrhage and rapidly progressive glomerulonephritis. The authors highlight the importance of early recognising drug-induced pulmonary-renal syndrome (PRS) in order to avoid unnecessary tests, a delay in the diagnosis and evolution to end-stage kidney disease or life-threatening conditions.


Subject(s)
Glomerulonephritis/chemically induced , Hemorrhage/chemically induced , Lung Diseases/chemically induced , Propylthiouracil/adverse effects , Aged, 80 and over , Female , Humans
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